Direct α-Alkylation of Ketones with Alcohols in Water

被引：94

作者：

Xu, Guoqiang ^{[1
]}

Li, Qiong ^{[1
,2
]}

Feng, Jiange ^{[2
]}

Liu, Qiang ^{[1
]}

Zhang, Zuojun ^{[1
]}

Wang, Xicheng ^{[1
]}

Zhang, Xiaoyun ^{[2
]}

Mu, Xindong ^{[1
]}

机构：

[1] Chinese Acad Sci, CAS Key Lab Biobased Mat, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China

[2] China Univ Petr, Coll Sci, Qingdao 266555, Peoples R China

来源：

CHEMSUSCHEM | 2014年 / 7卷 / 01期

关键词：

alcohols; alkylations; aqueous-phase reforming; heterogeneous catalysis; ketones; CATALYZED ALKYLATION; TRANSFORMATIONS; SOLVENT; FUELS;

D O I：

10.1002/cssc.201300815

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The direct alpha-alkylation of ketones with alcohols has emerged as a new green protocol to construct C-C bonds with H2O as the sole byproduct. In this work, a very simple and convenient Pd/C catalytic system for the direct alpha-alkylation of ketones with primary alcohols in pure water is developed. Based on this catalytic system, aqueous mixtures of dilute acetone, 1-butanol, and ethanol (mimicking ABE fermentation products) can be directly transformed into C-5-C-11 or longer-chain ketones and alcohols, which are precursors to fuels.

引用

页码：105 / 109

页数：5

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