Biomimetic Synthesis of ent-(-)-Azonazine and Stereochemical Reassignment of Natural Product

被引：66
作者：
Zhao, Ji-Chen [1 ]
Yu, Shun-Ming [1 ]
Liu, Yun [1 ]
Yao, Zhu-Jun [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 17期
关键词：
HYPERVALENT IODINE REAGENTS; DIAZONAMIDE; CONCISE; SALTS;
D O I：
10.1021/ol4015706
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first total synthesis of ent-(-)-azonazine has been accomplished using a hypervalent iodine-mediated biomimetic oxidative cyclization to construct the highly strained core. Based on the results from the completed synthesis, both the relative and absolute configurations of natural (+)-azonazine were revised.
引用
收藏
页码：4300 / 4303
页数：4
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