Non-motor symptoms of Parkinson's disease A review ... from the past

被引：75
作者：
Garcia-Ruiz, Pedro J. [1 ]
Chaudhuri, K. Ray [2 ]
Martinez-Martin, Pablo [3 ,4 ]
机构：
[1] Fdn Jimenez Diaz, Dept Neurol, E-28040 Madrid, Spain
[2] Kings Coll London, Kings Coll Hosp, Natl Parkinson Fdn Ctr Excellence, London WC2R 2LS, England
[3] Carlos III Inst Hlth, Alzheimer Ctr Reina Sofia Fdn, Madrid, Spain
[4] CIBERNED, Madrid, Spain
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2014年 / 338卷 / 1-2期
关键词：
History of Neurology; Motor and non-motor evaluation; Pain; Non-motor symptoms; Parkinson's disease; Classic literature; LEVODOPA; MOTOR;
D O I：
10.1016/j.jns.2014.01.002
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Although Parkinson's disease (PD) has been classically defined as a motor disorder, a range of non-motor symptoms (NMS) including cognitive, mood, autonomic and sleep disturbances occur with the passage of time. Although it seems that the non-motor aspect of PD is a recent observation, classic authors (James Parkinson, Charcot, Cowers, Oppenheim and Wilson) had described many NMS including pain, fatigue, bladder dysfunction, cognitive decline and delusion. In this review we have collated the classic literature of NMS in PD. (C) 2014 Elsevier B.V. All rights reserved.
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页码：30 / 33
页数：4
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