Strategies for Improving Animal Models for Regenerative Medicine

被引：67

作者：

Cibelli, Jose ^{[1
]}

Emborg, Marina E. ^{[2
,3
]}

Prockop, Darwin J. ^{[4
,5
]}

Roberts, Michael ^{[6
]}

Schatten, Gerald ^{[7
]}

Rao, Mahendra ^{[8
]}

Harding, John ^{[9
]}

Mirochnitchenko, Oleg ^{[9
]}

机构：

[1] Michigan State Univ, Cellular Reprogramming Lab, Dept Anim Sci, E Lansing, MI 48824 USA

[2] Univ Wisconsin, Dept Med Phys, Madison, WI 53715 USA

[3] Wisconsin Natl Primate Res Ctr, Madison, WI 53715 USA

[4] Texas A&M Hlth Sci Ctr, Coll Med, Temple, TX 76502 USA

[5] Inst Regenerat Med Scott & White, Dept Med, Temple, TX 76502 USA

[6] Univ Missouri, CS Bond Life Sci Ctr 240B, Columbia, MO 65211 USA

[7] Univ Pittsburgh, Dept Cell Biol & Physiol, Pittsburgh, PA 15261 USA

[8] NIH, Ctr Regenerat Med, Bethesda, MD 20892 USA

[9] NIH, Div Comparat Med ORIP DPCPSI OD, Bethesda, MD 20892 USA

来源：

CELL STEM CELL | 2013年 / 12卷 / 03期

关键词：

MYOCARDIAL-INFARCTION; CELLS;

D O I：

10.1016/j.stem.2013.01.004

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The field of regenerative medicine is moving toward translation to clinical practice. However, there are still knowledge gaps and safety concerns regarding stem cell-based therapies. Improving large animal models and methods for transplantation, engraftment, and imaging should help address these issues, facilitating eventual use of stem cells in the clinic.

引用

页码：271 / 274

页数：4

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