Glycosaminoglycans from chicken muscular stomach or gizzard

被引：1

作者：

Chen, Yin ^{[1
]}

Reddy, Megan ^{[2
,3
,4
,5
]}

Yu, Yanlei ^{[2
,3
,4
,5
]}

Zhang, Fuming ^{[2
,3
,4
,5
]}

Linhardt, Robert J. ^{[2
,3
,4
,5
]}

机构：

[1] Zhejiang Ocean Univ, Coll Food & Pharm, Zhoushan 316022, Peoples R China

[2] Rensselaer Polytech Inst, Dept Biol, Ctr Biotechnol & Interdisciplinary Studies, Troy, NY 12180 USA

[3] Rensselaer Polytech Inst, Dept Chem & Biol Engn, Ctr Biotechnol & Interdisciplinary Studies, Troy, NY 12180 USA

[4] Rensselaer Polytech Inst, Dept Biomed Engn, Ctr Biotechnol & Interdisciplinary Studies, Troy, NY 12180 USA

[5] Rensselaer Polytech Inst, Dept Chem & Chem Biol, Ctr Biotechnol & Interdisciplinary Studies, Troy, NY 12180 USA

来源：

GLYCOCONJUGATE JOURNAL | 2017年 / 34卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Glycosaminoglycans; Compositional analysis; Heparan sulfate; Chondroitin sulfate; Hyaluranan; Chicken gizzard; SULFATE; HEPARIN; EXPRESSION;

D O I：

10.1007/s10719-016-9737-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glycosaminoglycans (GAGs) were prepared from the muscular stomach or gizzard of the chicken. The content of GAGs on a dry weight basis contains 0.4 wt.% a typical value observed for a muscle tissue. The major GAG components were chondroitin-6-sulfate and chondroitin-4-sulfate (similar to 64 %) of molecular weight 21-22 kDa. Hyaluronan (similar to 24 %) had a molecular weight 120 kDa. Smaller amounts (12 %) of heparan sulfate was also present which was made of more highly sulfated chains of molecular weight of 21-22 kDa and a less sulfated low molecular weight (< 10 kDa) heterogeneous partially degraded heparan sulfate. Chicken gizzard represents an inexpensive and readily available source of muscle tissue-derived GAGs.

引用

页码：119 / 126

页数：8

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