Contrast-enhanced ultrasound mapping of sentinel lymph nodes in oral tongue cancer-a pilot study

被引：13
作者：
Gvetadze, Shalva R. [1 ,2 ,3 ]
Xiong, Ping [4 ]
Lv, Mingming [1 ]
Li, Jun [1 ]
Hu, Jingzhou [1 ]
Ilkaev, Konstantin D. [5 ]
Yang, Xin [1 ]
Sun, Jian [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Shanghai Key Lab Stomatol, Dept Oral Maxillofacial Head Neck Oncol,Sch Med, Shanghai, Peoples R China
[2] Cent Res Inst Dent & Maxillofacial Surg, Dept Reconstruct Maxillofacial Surg Microsurg & E, Moscow, Russia
[3] Cent Res Inst Dent & Maxillofacial Surg, Dept Consulting & Diagnost, Moscow, Russia
[4] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 9, Dept Ultrasound, Shanghai, Peoples R China
[5] NN Blokhin Russian Canc Res Ctr, Dept Head & Neck Surg, Moscow, Russia
来源：
DENTOMAXILLOFACIAL RADIOLOGY | 2017年 / 46卷 / 03期
关键词：
contrast-enhanced ultrasound; tongue squamous cell carcinoma; sentinel lymph node; SQUAMOUS-CELL CARCINOMA; BREAST-CANCER; INTRADERMAL MICROBUBBLES; MULTICENTER TRIAL; F-18-FDG PET/CT; SWINE MODEL; NECK-CANCER; FOLLOW-UP; BIOPSY; HEAD;
D O I：
10.1259/dmfr.20160345
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Objectives: To assess the usefulness of contrast-enhanced ultrasound (CEUS) with peritumoral injection of microbubble contrast agent for detecting the sentinel lymph nodes for oral tongue carcinoma. Methods: The study was carried out on 12 patients with T1-2cN0 oral tongue cancer. A radical resection of the primary disease was planned; a modified radical supraomohyoid neck dissection was reserved for patients with larger lesions (T2, n=8). The treatment plan and execution were not influenced by sentinel node mapping outcome. The Sonovue (TM) contrast agent (Bracco Imaging, Milan, Italy) was utilized. After detection, the position and radiologic features of the sentinel nodes were recorded. Results: The identification rate of the sentinel nodes was 91.7%; one patient failed to demonstrate any enhanced areas. A total of 15 sentinel nodes were found in the rest of the 11 cases, with a mean of 1.4 nodes for each patient. The sentinel nodes were localized in: Level IA-1 (6.7%) node; Level IB-11 (73.3%) nodes; Level IIA-3 (20.0%) nodes. No contrast-related adverse effects were observed. Conclusions: For oral tongue tumours, CEUS is a feasible and potentially widely available approach of sentinel node mapping. Further clinical research is required to establish the position of CEUS detection of the sentinel nodes in oral cavity cancers.
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页数：8
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