B cell precursors are targets for Salmonella infection

被引：38

作者：

Castro-Eguiluz, Denisse ^{[1
,4
]}

Pelayo, Rosana ^{[2
]}

Rosales-Garcia, Victor ^{[6
]}

Rosales-Reyes, Roberto ^{[3
,5
]}

Aipuche-Aranda, Celia ^{[3
]}

Ortiz-Navarrete, Vianney ^{[1
]}

机构：

[1] CINVESTAV, Dept Biomed Mol, Mexico City 07360, DF, Mexico

[2] Ctr Med Nacl Siglo XXI, Unidad Invest Med Enfermedades Oncol, Mexico City, DF, Mexico

[3] Univ Nacl Autonoma Mexico, Fac Med, Dept Expt Med, Mexico City, DF, Mexico

[4] IPN, Escuela Nacl Ciencias Biol, Dept Inmunol, Mexico City 07738, DF, Mexico

[5] Hosp Infantil Mexico Dr Federico Gomez, Unidad Invest Enfermedades Oncol, Mexico City, DF, Mexico

[6] CINVESTAV, Unidad Citometria Flujo, Mexico City 07360, DF, Mexico

来源：

MICROBIAL PATHOGENESIS | 2009年 / 47卷 / 01期

关键词：

Salmonella; B cells; Bone marrow; Progenitors; BONE-MARROW; TYPHOID-FEVER; PLASMA-CELL; MATURATION; SELECTION;

D O I：

10.1016/j.micpath.2009.04.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We previously reported that, in mice, B cells are a reservoir for bacteria during Salmonella infection. Here, we show that, within the bone marrow, B cells and their precursors are targeted for infection by Salmonella enterica serovar typhimurium. Our data suggest that B cells within the bone marrow may be a bacterial niche during chronic Salmonella infection. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：52 / 56

页数：5

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