Enhancing Quantum Dots for Bioimaging using Advanced Surface Chemistry and Advanced Optical Microscopy: Application to Silicon Quantum Dots (SiQDs)

被引：62

作者：

Cheng, Xiaoyu ^{[1
]}

Hinde, Elizabeth ^{[2
]}

Owen, Dylan M. ^{[2
]}

Lowe, Stuart B. ^{[1
]}

Reece, Peter J. ^{[3
]}

Gaus, Katharina ^{[2
]}

Gooding, J. Justin ^{[1
]}

机构：

[1] Univ New S Wales, ARC Ctr Excellence Convergent Bionano Sci & Techn, Australian Ctr NanoMed, Sch Chem, Sydney, NSW 2052, Australia

[2] Univ New S Wales, ARC Ctr Excellence Adv Mol Imaging, Sch Med Sci, EMBL Australia Node Single Mol Sci, Sydney, NSW 2052, Australia

[3] Univ New S Wales, Sch Phys, Sydney, NSW 2052, Australia

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 40期

基金：

澳大利亚研究理事会; 英国医学研究理事会;

关键词：

cancer; fluorescence lifetime imaging microscopy (FLIM); fluorescence; Forster resonance energy transfer (FRET); quantum dots; PHASOR APPROACH; MICROEMULSION SYNTHESIS; GREEN LUMINESCENCE; ENERGY-TRANSFER; NANOPARTICLES; FUNCTIONALIZATION; PHOTOLUMINESCENCE; NANOCRYSTALS; ORIGIN; ULTRABRIGHT;

D O I：

10.1002/adma.201503223

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluorescence lifetime imaging microscopy is successfully demonstrated in both one-and two-photon cases with surface modified, nanocrystalline silicon quantum dots in the context of bioimaging. The technique is further demonstrated in combination with Forster resonance energy transfer studies where the color of the nanoparticles is tuned by using organic dye acceptors directly conjugated onto the nanoparticle surface.

引用

页码：6144 / 6150

页数：7

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