Detection of blaSHV, blaTEM and blaCTX-M antibiotic resistance genes in randomly selected bacterial pathogens from the Steve Biko Academic Hospital

被引：32

作者：

Ehlers, Marthie M. ^{[1
]}

Veldsman, Chrisna ^{[1
]}

Makgotlho, Eddy P. ^{[1
]}

Dove, Michael G. ^{[1
]}

Hoosen, Anwar A. ^{[1
]}

Kock, Marleen M. ^{[1
]}

机构：

[1] Univ Pretoria NHLS, Fac Hlth Sci, Dept Med Microbiol, ZA-0001 Pretoria, South Africa

来源：

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2009年 / 56卷 / 03期

关键词：

extended-spectrum beta-lactamases; cefotaximase; temoniera; sulfhydryl variable; SPECTRUM BETA-LACTAMASES; ESCHERICHIA-COLI; MOLECULAR EPIDEMIOLOGY; INFECTION; EMERGENCE; ENTEROBACTERIACEAE; PREVALENCE; CHALLENGE;

D O I：

10.1111/j.1574-695X.2009.00564.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Extended-spectrum beta-lactamases (ESBLs) are considered to be one of the most important antibiotic resistance mechanisms. This study reported the ESBL-producing genes in 53 randomly selected clinical bacterial isolates from the Steve Biko Academic Hospital. The presence of the bla(SHV), bla(TEM) and bla(CTX-M) genes was determined, and the overall prevalence of these genes detected in this study was 87% (46/53) in comparison with the literature; these results were higher when compared with 33% for Escherichia coli in Europe and 0.8% in Denmark for similar pathogens. These research findings indicated that it is crucial to routinely monitor the prevalence of these resistance genes.

引用

页码：191 / 196

页数：6

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