Detection of blaSHV, blaTEM and blaCTX-M antibiotic resistance genes in randomly selected bacterial pathogens from the Steve Biko Academic Hospital

被引：30
作者：
Ehlers, Marthie M. [1 ]
Veldsman, Chrisna [1 ]
Makgotlho, Eddy P. [1 ]
Dove, Michael G. [1 ]
Hoosen, Anwar A. [1 ]
Kock, Marleen M. [1 ]
机构：
[1] Univ Pretoria NHLS, Fac Hlth Sci, Dept Med Microbiol, ZA-0001 Pretoria, South Africa
来源：
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2009年 / 56卷 / 03期
关键词：
extended-spectrum beta-lactamases; cefotaximase; temoniera; sulfhydryl variable; SPECTRUM BETA-LACTAMASES; ESCHERICHIA-COLI; MOLECULAR EPIDEMIOLOGY; INFECTION; EMERGENCE; ENTEROBACTERIACEAE; PREVALENCE; CHALLENGE;
D O I：
10.1111/j.1574-695X.2009.00564.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Extended-spectrum beta-lactamases (ESBLs) are considered to be one of the most important antibiotic resistance mechanisms. This study reported the ESBL-producing genes in 53 randomly selected clinical bacterial isolates from the Steve Biko Academic Hospital. The presence of the bla(SHV), bla(TEM) and bla(CTX-M) genes was determined, and the overall prevalence of these genes detected in this study was 87% (46/53) in comparison with the literature; these results were higher when compared with 33% for Escherichia coli in Europe and 0.8% in Denmark for similar pathogens. These research findings indicated that it is crucial to routinely monitor the prevalence of these resistance genes.
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收藏
页码：191 / 196
页数：6
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