Epigenetic Regulation of Gut Microbial Dysbiosis

被引：15
作者：
Srivastava, Shivani [1 ]
Singh, Archana [2 ]
Sandeep, Kumar [3 ]
Yadav, Durgavati [4 ]
机构：
[1] Ohio State Univ, Davis Heart & Lung Res Inst, Dept Physiol & Cell Biol, Wexner Med Ctr, Columbus, OH 43201 USA
[2] Banaras Hindu Univ, Mahila Mahavidyalaya, Dept Bioinformat, Varanasi 221005, Uttar Pradesh, India
[3] All India Inst Med Sci, Dr BR Ambedkar Inst Rotary Canc Hosp, New Delhi 110029, India
[4] All India Inst Med Sci, Dept Urol, New Delhi 110029, India
来源：
INDIAN JOURNAL OF MICROBIOLOGY | 2021年 / 61卷 / 02期
关键词：
Epigenetics; Dysbiosis; Human; Health; Disease; Microbiome; Microorganism; TRIMETHYLAMINE-N-OXIDE; ANTIMICROBIAL ACTIVITY; CROSSTALK; BACTERIAL; CELLS; LIVER; LINK;
D O I：
10.1007/s12088-021-00920-y
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Microbiota inside the gut plays a vital role in maintaining human health. Microbial dysbiosis is associated with various complications leading to a range of diseases. Epigenetic changes enforced by various environmental and lifestyle factors lead to heritable modifications. These epigenetic modifications include DNA methylation, histone modifications, chromatin remodelling, and ribonucleic acid-based mechanisms. This review summarizes the impacts of environmental factors on the gut microbiome, epigenetic modifications, and their role in cardiovascular diseases.
引用
收藏
页码：125 / 129
页数：5
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