Tau(273-284): A Molecular Dynamics Study of Intrinsically Disordered Protein Conformations in the Presence of Osmolytes

被引:0
|
作者
Levine, Zachary A. [1 ]
Larini, Luca [2 ]
Shea, Joan-Emma [1 ]
机构
[1] Univ Calif Santa Barbara, Santa Barbara, CA 93106 USA
[2] Rutgers State Univ, Piscataway, NJ USA
关键词
D O I
10.1016/j.bpj.2013.11.2729
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:483A / 483A
页数:1
相关论文
共 50 条
  • [1] Molecular Dynamics Simulations of a Powder Model of the Intrinsically Disordered Protein Tau
    Fichou, Yann
    Heyden, Matthias
    Zaccai, Giuseppe
    Weik, Martin
    Tobias, Douglas J.
    JOURNAL OF PHYSICAL CHEMISTRY B, 2015, 119 (39): : 12580 - 12589
  • [2] Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study
    Larini, Luca
    Gessel, Megan Murray
    LaPointe, Nichole E.
    Do, Thanh D.
    Bowers, Michael T.
    Feinstein, Stuart C.
    Shea, Joan-Emma
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2013, 15 (23) : 8916 - 8928
  • [3] Structure Solution of Misfolded Conformations Adopted by Intrinsically Disordered Alzheimer's Tau Protein
    Sevcik, Jozef
    Skrabana, Rostislav
    Kontsekova, Eva
    Novak, Michal
    PROTEIN AND PEPTIDE LETTERS, 2009, 16 (01): : 61 - 64
  • [4] Molecular dynamics simulations of the intrinsically disordered protein amelogenin
    Apicella, Alessandra
    Marascio, Matteo
    Colangelo, Vincenzo
    Soncini, Monica
    Gautieri, Alfonso
    Plummer, Christopher J. G.
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 35 (08): : 1813 - 1823
  • [5] Dynamics of an Intrinsically Disordered Protein Reveal Metastable Conformations That Potentially Seed Aggregation
    Qiao, Qin
    Bowman, Gregory R.
    Huang, Xuhui
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (43) : 16092 - 16101
  • [6] Conformations and exchange dynamics of FlgM, an intrinsically disordered protein, in dilute and crowded conditions
    Smith, Pieter
    Banks, Anthony
    Zhou, Huan-Xiang
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [7] Fast Motions Dominate Dynamics of Intrinsically Disordered Tau Protein at High Temperatures
    Abyzov, Anton
    Mandelkow, Eckhard
    Zweckstetter, Markus
    Rezaei-Ghaleh, Nasrollah
    CHEMISTRY-A EUROPEAN JOURNAL, 2023, 29 (17)
  • [8] Impact of In-Cell and In-Vitro Crowding on the Conformations and Dynamics of an Intrinsically Disordered Protein
    Konig, Iwo
    Soranno, Andrea
    Nettels, Daniel
    Schuler, Benjamin
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (19) : 10724 - 10729
  • [9] A Coarse-Grained Molecular Dynamics Approach to the Study of the Intrinsically Disordered Protein α-Synuclein
    Ramis, Rafael
    Ortega-Castro, Joaquin
    Casasnovas, Rodrigo
    Marino, Laura
    Vilanova, Bartolome
    Adrover, Miquel
    Frau, Juan
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2019, 59 (04) : 1458 - 1471
  • [10] Molecular Deformation Is a Key Factor in Screening Aggregation Inhibitor for Intrinsically Disordered Protein Tau
    Chai, Keke
    Yang, Jian
    Tu, Ying
    Wu, Junjie
    Fang, Kang
    Shi, Shuo
    Yao, Tianming
    ACS CENTRAL SCIENCE, 2024, 10 (03) : 717 - 728