Heterodimerization of VLDLR and LRP6: A novel mechanism for the inhibition of the Wnt/β-catenin pathway.

被引：0
|
作者：
Shin, Younghwa [1 ]
Lee, Kyungwon [2 ]
Cheng, Rui [1 ]
Park, Kyungmin [2 ]
Hu, Yang [1 ]
Mcbride, Jeffrey [2 ]
He, Xuemin [1 ]
Takahashi, Yusuke [3 ]
Ma, Jian-xing [1 ]
机构：
[1] Univ Oklahoma HCS, Physiol, Oklahoma City, OK USA
[2] Univ Oklahoma HSC, Cell Biol, Oklahoma City, OK USA
[3] Univ Oklahoma HSC, Endocrinol, Oklahoma City, OK USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2015年 / 56卷 / 07期
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
5443
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and β-catenin signaling
    Reinke, Lauren
    Lam, Anna P.
    Flozak, Annette S.
    Varga, John
    Gottardi, Cara J.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 470 (03) : 606 - 612
  • [32] The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling
    Ng, Victoria H.
    Spencer, Zachary
    Neitzel, Leif R.
    Nayak, Anmada
    Loberg, Matthew A.
    Shen, Chen
    Kassel, Sara N.
    Kroh, Heather K.
    An, Zhenyi
    Anthony, Christin C.
    Bryant, Jamal M.
    Lawson, Amanda
    Goldsmith, Lily
    Benchabane, Hassina
    Hansen, Amanda G.
    Li, Jingjing
    D'Souza, Starina
    Lebensohn, Andres M.
    Rohatgi, Rajat
    Weiss, William A.
    Weiss, Vivian L.
    Williams, Charles
    Hong, Charles C.
    Robbins, David J.
    Ahmed, Yashi
    Lee, Ethan
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [33] The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling
    Victoria H. Ng
    Zachary Spencer
    Leif R. Neitzel
    Anmada Nayak
    Matthew A. Loberg
    Chen Shen
    Sara N. Kassel
    Heather K. Kroh
    Zhenyi An
    Christin C. Anthony
    Jamal M. Bryant
    Amanda Lawson
    Lily Goldsmith
    Hassina Benchabane
    Amanda G. Hansen
    Jingjing Li
    Starina D’Souza
    Andres M. Lebensohn
    Rajat Rohatgi
    William A. Weiss
    Vivian L. Weiss
    Charles Williams
    Charles C. Hong
    David J. Robbins
    Yashi Ahmed
    Ethan Lee
    Nature Communications, 14
  • [34] Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
    Bilic, Josipa
    Huang, Ya-Lin
    Davidson, Gary
    Zimmermann, Timo
    Cruciat, Cristina-Maria
    Bienz, Mariann
    Niehrs, Christof
    SCIENCE, 2007, 316 (5831) : 1619 - 1622
  • [35] Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin
    Yamamoto, Hideki
    Komekado, Hideyuki
    Kikuchi, Akira
    DEVELOPMENTAL CELL, 2006, 11 (02) : 213 - 223
  • [36] Deletion of Wnt Receptors Lrp5 and Lrp6 or β-catenin in osteoclast precursors differentially affects skeletal development
    Weivoda, Megan
    Ruan, Ming
    Hachfeld, Christine
    Pederson, Larry
    Davey, Rachel
    Zajac, Jeffrey
    Kobayashi, Yasuhiro
    Williams, Bart
    Khosla, Sundeep
    Westendorf, Jennifer
    Oursler, Merry Jo
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S90 - S91
  • [37] LRP5 and LRP6 in Wnt Signaling: Similarity and Divergence
    Ren, Qian
    Chen, Jiongcheng
    Liu, Youhua
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
  • [38] Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis
    Ockeloen, Charlotte W.
    Khandelwal, Kriti D.
    Dreesen, Karoline
    Ludwig, Kerstin U.
    Sullivan, Robert
    van Rooij, Iris A. L. M.
    Thonissen, Michelle
    Swinnen, Steven
    Phan, Milien
    Conte, Federica
    Ishorst, Nina
    Gilissen, Christian
    Fuentes, Laury Roa
    van de Vorst, Maartje
    Henkes, Arjen
    Steehouwer, Marloes
    van Beusekom, Ellen
    Bloemen, Marjon
    Vankeirsbilck, Bruno
    Berge, Stefaan
    Hens, Greet
    Schoenaers, Joseph
    Vander Poorten, Vincent
    Roosenboom, Jasmien
    Verdonck, An
    Devriendt, Koen
    Roeleveldt, Nel
    Jhangiani, Shalini N.
    Vissers, Lisenka E. L. M.
    Lupski, James R.
    de Ligt, Joep
    Von den Hoff, Johannes W.
    Pfundt, Rolph
    Brunner, Han G.
    Zhou, Huiqing
    Dixon, Jill
    Mangold, Elisabeth
    van Bokhoven, Hans
    Dixon, Michael J.
    Kleefstra, Tjitske
    Hoischen, Alexander
    Carels, Carine E. L.
    GENETICS IN MEDICINE, 2016, 18 (11) : 1158 - 1162
  • [39] G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway
    Chen, Minyong
    Philipp, Melanie
    Wang, Jiangbo
    Premont, Richard T.
    Garrison, Tiffany R.
    Caron, Marc G.
    Lefkowitz, Robert J.
    Chen, Wei
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (50) : 35040 - 35048
  • [40] For Wnt Signaling, Fucosylation of LRP6 Is a Bitter Pill
    Shah, Adnan Shami
    Sun, Hongyan
    Baskin, Jeremy M.
    CELL CHEMICAL BIOLOGY, 2020, 27 (09): : 1114 - 1116
12345