Lesions of pemphigus vulgaris on irradiated skin

被引:8
作者
Aguado, L. [1 ]
Marquina, M. [1 ]
Pretel, M. [1 ]
Ruiz-Carrillo, G. [1 ]
Espana, A. [1 ]
机构
[1] Univ Navarra Clin, Dept Dermatol, Pamplona, Spain
关键词
X-RAY-IRRADIATION; THERAPY;
D O I
10.1111/j.1365-2230.2008.03084.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg) 3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy. We report a patient with a history of microprolactinoma and PV, who had only oral lesions from the beginning of her illness but 2 months after treatment with radiotherapy for a breast neoplasia, developed skin lesions limited to the irradiated area. Over the following few months, she also developed autoantibodies against Dsg1.
引用
收藏
页码:E148 / E150
页数:3
相关论文
共 10 条
[1]   The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile [J].
Amagai, M ;
Tsunoda, K ;
Zillikens, D ;
Nagai, T ;
Nishikawa, T .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 40 (02) :167-170
[2]   Epitope spreading: Lessons from autoimmune skin diseases [J].
Chan, LS ;
Vanderlugt, CJ ;
Hashimoto, T ;
Nishikawa, T ;
Zone, JJ ;
Black, MM ;
Wojnarowska, F ;
Stevens, SR ;
Chen, M ;
Fairley, JA ;
Woodley, DT ;
Miller, SD ;
Gordon, KB .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1998, 110 (02) :103-109
[3]   LINEAR PEMPHIGUS VULGARIS AFTER X-RAY-IRRADIATION [J].
CROVATO, F ;
DESIRELLO, G ;
NAZZARI, G ;
DEMARCHI, R .
DERMATOLOGICA, 1989, 179 (03) :135-136
[4]   INDUCTION OF PEMPHIGUS BY X-RAY-IRRADIATION [J].
DAVID, M ;
FEUERMAN, EJ .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1987, 12 (03) :197-199
[5]  
De Bellis Annamaria, 2005, Pituitary, V8, P25
[6]  
DELAPORTE E, 1991, ANN DERMATOL VENER, V118, P447
[7]   PEMPHIGUS VULGARIS FOLLOWING COBALT THERAPY FOR BRONCHIAL-CARCINOMA [J].
GIROLOMONI, G ;
MAZZONE, E ;
ZAMBRUNO, G .
DERMATOLOGICA, 1989, 178 (01) :37-38
[8]   IONIZING RADIATION-INDUCED PEMPHIGUS - CASE PRESENTATIONS AND LITERATURE-REVIEW [J].
LOW, GJ ;
KEELING, JH .
ARCHIVES OF DERMATOLOGY, 1990, 126 (10) :1319-1323
[9]  
Mseddi M, 2005, Cancer Radiother, V9, P96, DOI 10.1016/j.canrad.2004.10.007
[10]   Pemphigus vulgaris induced by diazinon and sun exposure [J].
Orion, E ;
Barzilay, D ;
Brenner, S .
DERMATOLOGY, 2000, 201 (04) :378-379