Derivative spectrophotometric determination of droperidol in presence of parabens

被引：17
|
作者：
Trabelsi, H [1 ]
Raouafi, F [1 ]
Limam, M [1 ]
Bouzouita, K [1 ]
机构：
[1] Lab Natl Controle Medicaments, Tunis, Tunisia
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2002年 / 29卷 / 1-2期
关键词：
droperidol; neuroleptic; derivative spectrophotometry;
D O I：
10.1016/S0731-7085(02)00095-X
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
We have developed a fast and accurate method for the determination of droperidol in the presence of methylparaben and propylparaben using derivative spectrophotometry. The first derivative amplitudes at 255.2 nm were selected for the assay. Calibration graph follows Beer's law in the range of 5-35 mug ml(-1). The coefficient of variation (CV) for intra-day and inter-day precision were less than 1.0 and 2.0%, respectively. The method was applied in the quality control of commercial oral and injection solutions and proved to be suitable for routine analysis. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：239 / 245
页数：7
相关论文
共 50 条
  • [21] Simultaneous derivative spectrophotometric determination of levodopa and carbidopa in pharmaceutical preparations
    Madrakian, T
    Afkhami, A
    Borazjani, M
    Bahram, M
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2004, 25 (12) : 1764 - 1768
  • [22] Derivative spectrophotometric methods for the determination of rhodium, palladium and platinum in mixtures
    Balcerzak, M
    Bystronska, D
    Swiecicka, E
    CHEMIA ANALITYCZNA, 2001, 46 (04): : 547 - 560
  • [23] Derivative spectrophotometric determination of nickel using Br-PADAP
    Ferreira, SLC
    Costa, ACS
    deJesus, DS
    TALANTA, 1996, 43 (10) : 1649 - 1656
  • [24] Determination of Tartrazine and Sunset Yellow in Foodstuffs by Derivative Spectrophotometric Method
    Saad, Antakli
    Nazira, Sarkis
    Rasha, Alsaleh
    ASIAN JOURNAL OF CHEMISTRY, 2011, 23 (04) : 1825 - 1828
  • [25] FIRST DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF FLUOXETINE HYDROCHLORIDE AND OLANZAPINE IN TABLETS
    Parmar, Vijaykumar K.
    Patel, Jatin N.
    Jani, Girish K.
    Prajapati, Laxman M.
    Gagoria, Jagbir
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (11): : 2996 - 3001
  • [26] DETERMINATION OF ANTHOCYANINS IN SOME VEGETABLES AND FRUITS BY DERIVATIVE SPECTROPHOTOMETRIC METHOD
    Sakar, Dolunay
    Karaoglan, Guelnur Keser
    Gumrukcu, Gulsah
    Ozgur, Mahmure Ustun
    REVIEWS IN ANALYTICAL CHEMISTRY, 2008, 27 (04) : 235 - 249
  • [27] Simultaneous determination of montelukast and loratadine by HPLC and derivative spectrophotometric methods
    Radhakrishna, T
    Narasaraju, A
    Ramakrishna, M
    Satyanarayana, A
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 31 (02) : 359 - 368
  • [28] DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF SOME TRANQUILIZER-ANTIDEPRESSANT MIXTURES
    ELYAZBI, FA
    KORANY, MA
    ABDINE, HH
    ELSAYED, MA
    SPECTROSCOPY LETTERS, 1991, 24 (03) : 437 - 449
  • [29] Determination of irbesartan in the presence of hydrochlorothiazide by derivative spectrophotometry
    Albero, I
    Ródenas, V
    García, S
    Sánchez-Pedreño, C
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 29 (1-2) : 299 - 305
  • [30] Voltammetric determination of droperidol and benperidol
    Biryol, I
    Ozkan, SA
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1997, 15 (11) : 1695 - 1701
12345