Mizoroki-Heck Reactions Catalysed by (N-Heterocyclic Carbene)PdCl2(Et3N) Complexes

被引：13

作者：

Gallop, Christopher W. D. ^{[1
]}

Zinser, Caroline ^{[1
]}

Guest, Daniel ^{[1
]}

Navarro, Oscar ^{[1
]}

机构：

[1] Univ Sussex, Dept Chem, Brighton BN1 9QJ, E Sussex, England

来源：

SYNLETT | 2014年 / 25卷 / 15期

关键词：

carbene; palladium; homogeneous catalysis; alkenes; halides; N-HETEROCYCLIC CARBENE; ARYL CHLORIDES; ARYLATION; EFFICIENT;

D O I：

10.1055/s-0034-1378447

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Complexes of general formula (NHC)PdCl2(Et3N) were used as pre-catalysts in Mirozoki-Heck couplings of activated aryl chlorides and deactivated aryl bromides as electrophiles, without the need of an inert atmosphere and in relatively short reaction times. The protocol was extended to the use of microwave heating, reducing further the reaction times with no detriment in the yields of the desired products.

引用

页码：2225 / 2228

页数：4

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