Recent results on the development of a proton computed tomography system

被引：28

作者：

Civinini, C. ^{[1
]}

Bruzzi, M. ^{[1
,2
]}

Bucciolini, M. ^{[1
,3
,4
]}

Carpinelli, M. ^{[5
,6
]}

Cirrone, G. A. P. ^{[7
]}

Cuttone, G. ^{[7
]}

Lo Presti, D. ^{[8
,9
]}

Pallotta, S. ^{[1
,3
,4
]}

Pugliatti, C. ^{[8
,9
]}

Randazzo, N. ^{[8
]}

Romano, F. ^{[7
,10
,11
]}

Scaringella, M. ^{[12
]}

Sipala, V. ^{[5
,6
]}

Stancampiano, C. ^{[8
,9
]}

Talamonti, C. ^{[1
,3
,4
]}

Vanzi, E. ^{[4
]}

Zani, M. ^{[1
,3
]}

机构：

[1] Ist Nazl Fis Nucl, Sez Firenze, Florence, Italy

[2] Univ Florence, Dipartimento Fis & Astron, Florence, Italy

[3] Univ Florence, Dipartimento Sci Biomed Sperimentali & Clin, Florence, Italy

[4] Azienda Osped Univ Careggi, SOD Fis Med, Florence, Italy

[5] Ist Nazl Fis Nucl, Sez Cagliari, Cagliari, Italy

[6] Univ Sassari, Dipartimento Chim & Farm, I-07100 Sassari, Italy

[7] Ist Nazl Fis Nucl, Lab Nazl Sud, I-95129 Catania, Italy

[8] Ist Nazl Fis Nucl, Sez Catania, I-95129 Catania, Italy

[9] Univ Catania, Dipartimento Fis & Astron, Catania, Italy

[10] Museo Stor Fis, Rome, Italy

[11] Ctr Studi & Ric Enrico Fermi, Rome, Italy

[12] Univ Florence, Dipartimento Ingn Ind, Florence, Italy

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2013年 / 732卷

关键词：

Silicon microstrip tracker; Calorimetry; Proton computed tomography;

D O I：

10.1016/j.nima.2013.05.147

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Proton Computed Tomography (pCT) is a medical imaging technique based on the use of proton beams with energies above 200 MeV to directly measure stopping power distributions inside the tissue volume. PRIMA (PRoton IMAging) is an Italian collaboration working on the development of a pCT scanner based on a tracker and a calorimeter to measure single protons trajectory and residual energy. The tracker is composed of four planes of silicon microstrip detectors to measure proton entry and exit positions and angles. Residual energy is measured by a calorimeter composed of YAG:Ce scintillating crystals. A first prototype of pCT scanner, with an active area of about 5 x 5 cm(2), has been constructed and characterized with 60 MeV protons at the INFN Laboratori Nazionali del Sud, Catania (Italy) and with 180 MeV protons at Svedberg Laboratory, Uppsala (Sweden). A new pre-clinical prototype with an extended active area up to 20 x 5 cm(2), real time data acquisition and a data rate up to 1 MHz is under development. A description of the two prototypes will be presented together with first results concerning tomographic image reconstruction. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：573 / 576

页数：4

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