Nitric oxide and portal hypertension: Its role in the regulation of intrahepatic and splanchnic vascular resistance

被引：115
作者：
Wiest, R
Groszmann, RJ
机构：
[1] Vet Adm CT Healthcare Syst, Hepat Hemodynam Lab, West Haven, CT 06516 USA
[2] Yale Univ, Sch Med, Dept Digest Dis, New Haven, CT USA
来源：
SEMINARS IN LIVER DISEASE | 1999年 / 19卷 / 04期
关键词：
nitric oxide; portal hypertension; liver cirrhosis; hyperdynamic circulation;
D O I：
10.1055/s-2007-1007129
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
In recent years if has become well established that nitric oxide (NO) plays a crucial role in the hemodynamic abnormalities that develop in chronic portal hypertension. The purpose of this review is to summarize the available data and current concepts regarding the involvement of NO in the pathophysiologic changes in the microcirculation of the liver and the splanchnic and systemic circulation that associate portal hypertension.
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收藏
页码：411 / 426
页数：16
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