Gastric signet ring cell adenocarcinoma: A distinct entity

被引：4
作者：
Tabouret, Tessa [1 ]
Dhooge, Marion [1 ,2 ]
Rouquette, Alexandre [3 ]
Brezault, Catherine [1 ]
Beuvon, Frederic [3 ]
Chaussade, Stanislas [1 ,2 ]
Coriat, Romain [1 ,2 ]
机构：
[1] CHU Cochin Port Royal, Serv Gastroenterol, F-75014 Paris, France
[2] Univ Paris 05, Sorbonne Paris Cite, Fac Med, AP HP, F-75006 Paris, France
[3] CHU Cochin Port Royal, Serv Anatomopathol, F-75014 Paris, France
来源：
PRESSE MEDICALE | 2014年 / 43卷 / 04期
关键词：
RISK-FACTORS; CARCINOMA; CANCER; 5-FLUOROURACIL; GASTRECTOMY; HISTOLOGY; RESECTION; FEATURES; IMPACT;
D O I：
10.1016/j.lpm.2013.07.024
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Gastric signet ring cell carcinoma (GSRC) is a distinct entity. Their incidence is increasing. The pathologist plays a central role in the identification of this entity. Diagnosis is based on an adenocarcinoma containing a majority of signet ring cells (above 50 %). The prognosis of GSRC is the same as gastric adenocarcinoma while GSRC appeared more aggressive. Signet ring cells present a low sensitivity to chemotherapy. This review aimed to discuss the histological, the prognostic and the therapeutic aspect of this entity.
引用
收藏
页码：353 / 357
页数：5
相关论文
共 27 条
[1]   Subtotal versus total gastrectomy for gastric cancer -: Five-year survival rates in a multicenter randomized Italian trial [J].
Bozzetti, F ;
Marubini, E ;
Bonfanti, G ;
Miceli, R ;
Piano, C ;
Gennari, L .
ANNALS OF SURGERY, 1999, 230 (02) :170-178
[2]   Early Signet Ring Cell Gastric Cancer [J].
Chiu, Cheng-Tang ;
Kuo, Chia-Jung ;
Yeh, Ta-Sen ;
Hsu, Jun-Te ;
Liu, Keng-Hao ;
Yeh, Chun-Nan ;
Hwang, Tsann-Long ;
Jan, Yi-Yin ;
Lin, Chun-Jung .
DIGESTIVE DISEASES AND SCIENCES, 2011, 56 (06) :1749-1756
[3]   Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer [J].
Cunningham, David ;
Allum, William H. ;
Stenning, Sally P. ;
Thompson, Jeremy N. ;
Van de Velde, Cornelis J. H. ;
Nicolson, Marianne ;
Scarffe, J. Howard ;
Lofts, Fiona J. ;
Falk, Stephen J. ;
Iveson, Timothy J. ;
Smith, David B. ;
Langley, Ruth E. ;
Verma, Monica ;
Weeden, Simon ;
Chua, Yu Jo .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (01) :11-20
[4]   Minilaparoscopy in the diagnosis of peritoneal tumor spread - Prospective controlled comparison with computed tomography [J].
Denzer, U ;
Hoffmann, S ;
Helmreich-Becker, I ;
Kauczor, HU ;
Thelen, M ;
Kanzler, S ;
Galle, PR ;
Lohsel, AN .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2004, 18 (07) :1067-1070
[5]   TOTAL VERSUS SUBTOTAL GASTRECTOMY FOR ADENOCARCINOMA OF THE GASTRIC ANTRUM - A FRENCH PROSPECTIVE CONTROLLED-STUDY [J].
GOUZI, JL ;
HUGUIER, M ;
FAGNIEZ, PL ;
LAUNOIS, B ;
FLAMANT, Y ;
LACAINE, F ;
PAQUET, JC ;
HAY, JM .
ANNALS OF SURGERY, 1989, 209 (02) :162-166
[6]   Indication for endoscopic mucosal resection in early signet ring cell gastric cancer [J].
Ha, T. K. ;
An, J. Y. ;
Youn, H. K. ;
Noh, J. H. ;
Sohn, T. S. ;
Kim, S. .
ANNALS OF SURGICAL ONCOLOGY, 2008, 15 (02) :508-513
[7]   Risk factors of peritoneal recurrence in eso-gastric signet ring cell adenocarcinoma: Results of a multicentre retrospective study [J].
Honore, C. ;
Goere, D. ;
Messager, M. ;
Souadka, A. ;
Dumont, F. ;
Piessen, G. ;
Elias, D. ;
Mariette, C. .
EJSO, 2013, 39 (03) :235-241
[8]   Signet ring cell mixed histology may show more aggressive behavior than other histologies in early gastric cancer [J].
Huh, Cheal Wung ;
Jung, Da Hyun ;
Kim, Jie-Hyun ;
Lee, Yong Chan ;
Kim, Hyunki ;
Kim, Hoguen ;
Yoon, Sun Och ;
Youn, Young Hoon ;
Park, Hyojin ;
Lee, Sang In ;
Choi, Seung Ho ;
Cheong, Jae-Ho ;
Noh, Sung Hoon .
JOURNAL OF SURGICAL ONCOLOGY, 2013, 107 (02) :124-129
[9]   E-Cadherin Deficiency Initiates Gastric Signet-Ring Cell Carcinoma in Mice and Man [J].
Humar, Bostjan ;
Blair, Vanessa ;
Charlton, Amanda ;
More, Helen ;
Martin, Iain ;
Guilford, Parry .
CANCER RESEARCH, 2009, 69 (05) :2050-2056
[10]   The difference in clinic-pathological features between signet ring cell carcinoma and gastric mucinous adenocarcinoma [J].
Jiang, Hao ;
Zhang, Hongfeng ;
Tian, Lantian ;
Zhang, Xi ;
Xue, Yingwei .
TUMOR BIOLOGY, 2013, 34 (05) :2625-2631
123