Synthesis, characterization and antimicrobial activities of transition metal complexes of N,N-dialkyl-N′-(2-chlorobenzoyl)thiourea derivatives

N, N-di-n-propyl-N'-(2-chlorobenzoyl) thiourea (HL1) (1), N, N-diphenyl-N'-(2-chlorobenzoyl) thiourea (HL2) (2), and their Ni-II, Co-II, Cu-II, Zn-II, Pt-II, Cd-II and Pd-II complexes have been synthesized and characterized. HL1 and its copper complex were characterized by single-crystal X-ray diffraction methods. The ligands coordinate as bidentates yielding essentially neutral complexes of the type [ML2]. The complexes were screened for their in vitro antibacterial, antifungal activities and toxicity. All compounds showed antimicrobial activity, but antibacterial efficacy is greater than antifungal activity.