Discovery and Optimization of a TRAIL R2 Agonist for Cancer Therapy

被引：18
|
作者：
Angell, Yvonne M. [1 ]
Bhandari, Ashok [1 ]
De Francisco, M. Nuria [1 ]
Frederick, Brian T. [1 ]
Green, Jennifer M. [1 ]
Leu, Karen [1 ]
Leuther, Kerstin [1 ]
Sana, Reuben [1 ]
Schatz, Peter J. [1 ]
Whitehorn, Erik A. [1 ]
Wright, Kathy [1 ]
Holmes, Christopher P. [1 ]
机构：
[1] Affymax Inc, Palo Alto, CA 94304 USA
来源：
PEPTIDES FOR YOUTH | 2009年 / 611卷
关键词：
RECEPTOR; APOPTOSIS; FAMILY; DEATH;
D O I：
10.1007/978-0-387-73657-0_45
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：101 / 103
页数：3
相关论文
共 50 条
  • [1] Discovery and optimization of a TRAIL R2 agonist for cancer therapy
    Angell, Yvonne M.
    Bhandari, Ashok
    Chakrabarti, Anjan
    De Francisco, M. Nuria
    Duguay, Amy N.
    Frederick, Brian T.
    Leu, Karen
    Leuther, Kerstin
    Li, Xianfeng
    Penta, Kalyani
    Piplani, Sunila
    Sana, Reuben
    Whitehorn, Erik A.
    Schatz, Pete J.
    Yin, Kevin
    Holmes, Christopher P.
    UNDERSTANDING BIOLOGY USING PEPTIDES, 2006, : 405 - +
  • [2] Development of a TRAIL-R2 synthetic agonist for cancer therapy
    Angell, YM
    Chakrabarti, A
    DeFrancisco, MN
    Duguay, AN
    Frederick, BT
    Leuther, K
    Li, X
    Penta, K
    Piplani, S
    Sana, R
    Schatz, PJ
    Whitehorn, EA
    Wright, KL
    Yin, K
    Holmes, CP
    BIOPOLYMERS, 2005, 80 (04) : 556 - 556
  • [3] Expression and prognostic value of TRAIL receptors R1 and R2 in early stage breast cancer.
    McCarthy, MM
    Divito, KA
    Camp, RL
    Sznol, M
    Rimm, DL
    Kluger, HM
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 843S - 843S
  • [4] Revisiting the role of TRAIL/TRAIL-R in cancer biology and therapy
    Singh, Deepika
    Tewari, Mallika
    Singh, Sunita
    Narayan, Gopeshwar
    FUTURE ONCOLOGY, 2021, 17 (05) : 581 - 596
  • [5] Development of TRAIL-R2 synthetic trimer agonists for cancer therapy
    Angell, Y. M.
    Frederick, B. T.
    Green, J.
    Schatz, P. J.
    Whitehorn, E. A.
    Wright, K. L.
    Holmes, C. H.
    BIOPOLYMERS, 2007, 88 (04) : 532 - 532
  • [6] Antibodies to TRAIL receptors TRAIL-R1 and R2 induce apoptosis in non-Hodgkin's lymphoma cells
    Smith, MR
    Jin, F
    Joshi, I
    BLOOD, 2004, 104 (11) : 899A - 899A
  • [7] Echo-spacing optimization for the simultaneous measurement of reversible (R2′) and irreversible (R2) transverse relaxation rates
    Song, Ruitian
    Song, Hee Kwon
    MAGNETIC RESONANCE IMAGING, 2007, 25 (01) : 63 - 68
  • [8] R2
    ROLL, R
    JOURNAL OF FINANCE, 1988, 43 (03): : 541 - 566
  • [9] Bootstrapping R2 and adjusted R2 in regression analysis
    Ohtani, K
    ECONOMIC MODELLING, 2000, 17 (04) : 473 - 483
  • [10] Injectivity of differentiable maps R2 → R2 at infinity
    Gutierrez, Carlos
    Rabanal, Roland
    BULLETIN OF THE BRAZILIAN MATHEMATICAL SOCIETY, 2006, 37 (02): : 217 - 239
12345