The microbiome and its impact on food allergy and atopic dermatitis in children

被引：17

作者：

Los-Rycharska, Ewa ^{[1
]}

Golebiewski, Marcin ^{[2
,3
]}

Grzybowski, Tomasz ^{[4
]}

Rogalla-Ladniak, Urszula ^{[4
]}

Krogulska, Aneta ^{[1
]}

机构：

[1] Nicolaus Copernicus Univ Torun, Coll Med Bydgoszcz, Dept Paediat Allergol & Gastroenterol, Torun, Poland

[2] Nicolaus Copernicus Univ, Interdisciplinary Ctr Modern Technol, Torun, Poland

[3] Nicolaus Copernicus Univ, Chair Plant Physiol & Biotechnol, Torun, Poland

[4] Nicolaus Copernicus Univ Torun, Coll Med Bydgoszcz, Chair Forens Med, Torun, Poland

来源：

POSTEPY DERMATOLOGII I ALERGOLOGII | 2020年 / 37卷 / 05期

关键词：

microbiome; food allergy; atopic dermatitis; infants; GUT MICROBIOTA; SKIN MICROBIOME; COWS MILK; PROBIOTIC SUPPLEMENTATION; INTESTINAL MICROBIOTA; FECAL MICROBIOTA; BREAST-MILK; INFANTS; SENSITIZATION; BACTERIA;

D O I：

10.5114/ada.2019.90120

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Food allergy (FA) affects 4-10% of children, especially children with atopic dermatitis (AD). During infancy the gut microbiome may determine both the course of FA and tolerance to food allergens. Analogically, the skin microbiome changes in the course of AD. Most studies have associated FA with a lower abundance and diversity of Lactobacillales and Clostridiales, but greater numbers of Enterobacterales, while AD in children has been associated with lower numbers of Staphylococcus epidermidis and S. hominis but an abundance of S. aureus and Streptococcus species. An understanding of the impact of the microbiome on the clinical course of FA and AD may allow for the development of new models of allergy treatment and prevention.

引用

页码：641 / 650

页数：10

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