Evolution of CPV-2 and implicance for antigenic/genetic characterization

被引:60
作者
Martella, Vito [1 ]
Decaro, Nicola [1 ]
Buonavoglia, Canio [1 ]
机构
[1] Univ Bari, Fac Vet Med, Dept Anim Hlth & Wellbeing, I-70010 Bari, Italy
关键词
canine parvovirus; CPV-2; characterization; antigenic variant; evolution;
D O I
10.1007/s11262-005-0034-8
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A few amino acid differences in the viral protein VP2 account for important antigenic and biological changes among feline parvovirus (FPV), canine parvovirus (CPV-2) and CPV-2 variants 2a and 2b. Several pieces of evidence suggest that CPV-2 is still evolving as additional amino acid changes occurred within the main antigenic regions of CPV-2 capsid, altering the antigenic profile of the virus and stressing the need for implementing the diagnostic assays.
引用
收藏
页码:11 / 13
页数:3
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