Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19

被引:6
作者
Osawa, Kenta [1 ]
Sugiyama, Atsuhiko [1 ]
Uzawa, Akiyuki [1 ]
Hirano, Shigeki [1 ]
Yamamoto, Tatsuya [1 ,2 ]
Nezu, Masahiko [3 ]
Araki, Nobuyuki [1 ]
Kano, Hiroki [1 ]
Kuwabara, Satoshi [1 ]
机构
[1] Chiba Univ, Grad Sch Med, Dept Neurol, Chiba, Japan
[2] Chiba Prefectural Univ Hlth Sci, Dept Rehabil, Div Occupat Therapy, Chiba, Japan
[3] Chiba Univ Hosp, Dept Kampo Med, Chiba, Japan
关键词
myoclonus; ataxia; brain perfusion; COVID-19; Kampo; CEREBELLUM; DISTINCT; MOTOR;
D O I
10.2169/internalmedicine.9171-21
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Myoclonus and ataxia, with or without opsoclonus, have recently been recognized as a central nervous system syndrome associated with coronavirus disease-2019 (COVID-19). A 52-year-old Japanese man developed myoclonus and ataxia 16 days after the onset of COVID-19. Brain single-photon emission computed tomography (SPECT) revealed hyperperfusion in the cerebellum and hypoperfusion in the cerebral cortices with frontal predominance during the acute stage, which improved over two months. This study indicates that brain perfusion SPECT can be effective in detecting functional alterations in COVID-19-related myoclonus and ataxia.
引用
收藏
页码:1071 / 1076
页数:6
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