Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty

被引:15
作者
Qin, Chenglu [1 ,2 ,3 ,4 ]
Luo, Guangnan [3 ,4 ]
Luo, Xin [1 ,2 ]
Lifschutz, Brian N. [6 ]
Zhu, Ziwen [5 ,6 ]
Fang, Yujiang [5 ,6 ]
机构
[1] Jinan Univ, Affiliated Hosp 1, Dept Gynecol, Guangzhou, Guangdong, Peoples R China
[2] Jinan Univ, Affiliated Hosp 1, Dept Obstet, Guangzhou, Guangdong, Peoples R China
[3] Luohu Hosp, Dept Gynecol, Shenzhen, Peoples R China
[4] Luohu Hosp, Dept Obstet, Shenzhen, Peoples R China
[5] Des Moines Univ, Dept Microbiol Immunol & Pathol, Des Moines, IA 50312 USA
[6] Univ Missouri, Sch Med, Dept Surg, Columbia, MO 65212 USA
关键词
D O I
10.1038/s41598-019-44511-w
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
To investigate the artificial vaginal microecological features in patients who underwent laparoscopic peritoneal vaginoplasty. 54 cases of patients with artificial vagina after laparoscopic peritoneal vaginoplasty were included in this study. Microecosystem evaluation was performed. Artificial vaginal functional tests and biopsy from vaginal walls were performed. After laparoscopic peritoneal vaginoplasty, the artificial vaginal flora intensity was level II similar to III (88.9%); the vaginal flora diversity was level II similar to III (72.2%); the predominant vaginal bacteria were gram-positive macrobacillus (27.8%); approximately 57.4% of the patients had vaginal pH <= 4.5; there was no pathogenic bateria or other pathogens; dysbiosis accounted for 53.7% of the patients (64.5% of the patients who had the vaginoplasty operation less than 2 years ago exhibited dysbiosis; 39.1% of the patients who had the operation at least 2 years ago exhibited dysbiosis). Vaginal dysbiosis is common after laparoscopic peritoneal vaginoplasty. However, as time goes by, the artificial vaginal microecological condition gradually becomes normal. Evaluation of vaginal microenvironment after laparoscopic peritoneal vaginoplasty might play an important role in reproductive tract infection prevention and neovagina health care.
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页数:5
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