A Single Dose of Oral Sucrose Is Enough to Control Pain During Venipuncture: A Randomized Controlled Trial

被引：1

作者：

Cavicchiolo, Maria Elena ^{[1
]}

Daverio, Marco ^{[2
]}

Battajon, Nadia ^{[3
]}

Frigo, Anna Chiara ^{[4
]}

Lago, Paola ^{[1
,3
]}

机构：

[1] Univ Padua, Dept Womans & Childs Hlth, Neonatal Intens Care Unit, Padua, Italy

[2] Univ Padua, Dept Womans & Childs Hlth, Paediat Intens Care Unit, Padua, Italy

[3] Azienda Unita Locale Socio Sanit ULSS 2 Marca Tre, Neonatal Intens Care Unit, Treviso, Italy

[4] Univ Padua, Dept Cardiac Thorac Vasc Sci & Publ Hlth, Padua, Italy

来源：

FRONTIERS IN PAIN RESEARCH | 2022年 / 3卷

关键词：

preterm; pain; skin breaking procedures; sucrose; non-pharmacologic treatment;

D O I：

10.3389/fpain.2022.888076

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sucrose is effective in reducing pain during minor procedures in neonates. We evaluated whether a second dose of sucrose was more effective than a single dose during venipuncture. We performed a randomised, double-blind, controlled trial at the NICU of Padua Hospital (August 2016-October 2017). We randomised 72 preterm infants undergoing venipuncture for routine test to a control group, which received a single standard dose of sucrose 2 ' before the procedure and a placebo 30 '' after the venipuncture, and an experimental group in which they received two doses of 24% sucrose 2 ' before and 30 '' after the venipuncture. No difference in pain perception was found between the groups at 30 '', 60 '' and 120 ''. In conclusion, we do not recommend a second dose of sucrose during venipuncture in prematures.

引用

页数：3

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