Fecundity and life span in transgenic Drosophila melanogaster overexpressing hsp70

被引:12
|
作者
Minois, N [1 ]
Vaynberg, S [1 ]
机构
[1] Univ Minnesota, Dept Ecol Evolut & Behav, Minneapolis, MN 55455 USA
关键词
Drosophila melanogaster; fecundity; hsp70; overexpression; life span;
D O I
10.1023/A:1020103518664
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
In the present study, we investigated the effect of hsp70 overexpression on some life history components in transgenic fruit flies. We measured life span in mated flies and fecundity in flies subjected or not subjected to a heat shock inducing hsp70. Heat shock increased life span of the parental line, but not of the transgenic lines. Genetic manipulation of the flies altered their fecundity, but the heat shock had no effect on fecundity. To conclude, we have observed some costs of genetic manipulation by itself on life span and fecundity. However, the overexpression of the hsp70 extra copies by the exposure to heat did not alter the studied variables.
引用
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页码:301 / 306
页数:6
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