Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 β-lactamases in New York City

被引：369
|
作者：
Bradford, PA
Bratu, S
Urban, C
Visalli, M
Mariano, N
Landman, D
Rahal, JJ
Brooks, S
Cebular, S
Quale, J
机构：
[1] SUNY Downstate, Div Infect Dis, Brooklyn, NY 11203 USA
[2] Wyeth Res, Pearl River, NY USA
[3] Kingsbrook Jewish Med Ctr, Brooklyn, NY USA
[4] New York Hosp Queens, Flushing, NY USA
来源：
CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 01期
关键词：
D O I：
10.1086/421495
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Nineteen isolates of carbapenem-resistant Klebsiella species were recovered from 7 hospitals in New York City. Most K. pneumoniae belonged to a single ribotype. Nucleotide sequencing identified KPC-2, a carbapenemhydrolyzing beta-lactamase. In 3 strains, TEM-30, an inhibitor-resistant beta-lactamase, was detected. Carbapenem-resistant Klebsiella species possessing KPC-2 are endemic in New York City. This study documents the identification of an inhibitor-resistant TEM beta-lactamase in the United States.
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收藏
页码：55 / 60
页数：6
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