An 'oligarchy' rules neural development

被引：142
作者：
Rowitch, DH
Lu, QR
Kessaris, N
Richardson, WD
机构：
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
[3] UCL, Wolfson Inst Biomed Res, London WC1E 6BT, England
[4] UCL, Dept Biol, London WC1E 6BT, England
来源：
TRENDS IN NEUROSCIENCES | 2002年 / 25卷 / 08期
关键词：
D O I：
10.1016/S0166-2236(02)02201-4
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Recent reports show that Olig genes, which encode the basic helix-loop-helix Olig transcription factors, are essential for development of oligodendrocytes. Surprisingly, Olig function is also required for formation of somatic motor neurons. These findings alter our views of how the oligodendrocyte lineage is generated and raise further questions about the underlying developmental relationships between neurons and glia.
引用
收藏
页码：417 / 422
页数：6
相关论文
共 53 条
[1]   Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain [J].
Alberta, JA ;
Park, SK ;
Mora, J ;
Yuk, DI ;
Pawlitzky, I ;
Iannarelli, P ;
Vartanian, T ;
Stiles, CD ;
Rowitch, DH .
MOLECULAR AND CELLULAR NEUROSCIENCE, 2001, 18 (04) :434-441
[2]   Stem cells and pattern formation in the nervous system: The possible versus the actual [J].
Anderson, DJ .
NEURON, 2001, 30 (01) :19-35
[3]   Neuronal and glial cell biology [J].
Barres, BA ;
Barde, YA .
CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (05) :642-648
[4]   A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube [J].
Briscoe, J ;
Pierani, A ;
Jessell, TM ;
Ericson, J .
CELL, 2000, 101 (04) :435-445
[5]   Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis [J].
Chang, A ;
Tourtellotte, WW ;
Rudick, R ;
Trapp, BD .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (03) :165-173
[6]  
Doe CQ, 1998, J NEUROBIOL, V36, P111, DOI 10.1002/(SICI)1097-4695(199808)36:2<111::AID-NEU2>3.0.CO
[7]  
2-4
[8]  
Fu H, 2002, DEVELOPMENT, V129, P681
[9]  
FULTON BP, 1991, ANN NY ACAD SCI, V633, P27
[10]   Multipotent stem cells from the mouse basal forebrain contribute GABAergic neurons and oligodendrocytes to the cerebral cortex during embryogenesis [J].
He, WL ;
Ingraham, C ;
Rising, L ;
Goderie, S ;
Temple, S .
JOURNAL OF NEUROSCIENCE, 2001, 21 (22) :8854-8862
123456