Epilepsy in India: Nuptiality behaviour and fertility

Purpose: The study was conducted to assess the marital status and fertility in adults with epilepsy. Methods: The study group consisted of 240 subjects with epilepsy aged 15 and above, Unmarried mates (m) 55, unmarried females (f) 73 and married mates 48, married females 64. Data was collected according to standard protocol regarding age, sex, age at marriage and onset of seizure, effect of epilepsy on marriage, type of seizure and control, fertility pattern and abortions. The study group was followed up for 30 months. The data was compared with latest available state and national data using Student's 't'-test, chi square, Fisher Z-test. Results: The mean age of married subjects was 26.19 + 6.2 years and of the unmarried was 24.94 +/- 7.1 years. People with epilepsy had significantly (p < 0.05) higher mean age at marriage, significantly (p < 0.05) Lower rate of marriage (m 46.6% f 46.72%), significantly (p < 0.05) higher divorce rate and withheld marriage. Females compared to mates had higher divorce rate (f 5.84%) and withheld marriage (m 5.45% f 10.96%). The marriage rate of subjects with onset of epilepsy in the first decade (m 38.71 % f 34.09%) and second decade (m 33.33% f 35.42%) was significantly Lower (p < 0.05) than that of subjects with age at onset of epilepsy greater than 20 years (m 66.67% f 71.11 %). Subjects with epilepsy not in remission had significantly (p < 0.05) higher mean age at marriage, tower marriage rate and lower fertility per person-year of marriage than those in remission. Majority (95.54%) did not disclose epilepsy before marriage. Total fertility rate (TFR) in mates (4.56) and females (5.45) with epilepsy was comparable to general population. Abortions per pregnancy were 4.76%. Conclusion: Subjects with epilepsy had tower marriage prevalence rate, delayed marriage (especially females), withheld marriage and higher divorce rate compared to general population. Marriage rate was Lower in people with age at onset of epilepsy less than 20 years and in whom seizures were not in remission. Majority of people with epilepsy did not disclose epilepsy before marriage. Though fertility was not affected in people with epilepsy as compared to general population, mates had lower fertility than females. (C) 2006 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.