Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis .3. Physico-chemical properties and structure determination

被引：15
作者：
Matsumoto, N
Tsuchida, T
Sawa, R
Iinuma, H
Nakamura, H
Naganawa, H
Sawa, T
Takeuchi, T
机构：
[1] Institute of Microbial Chemistry, 3-14-23 Kamiosaki, Shinagawa-ku
来源：
JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 11期
关键词：
D O I：
10.7164/antibiotics.50.912
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The structures of epoxyquinomicins A (1), B (2), C (3) and D (4) were determined by spectroscopic studies. Compound 1 was determined to be (5R,6S)-2-(3-chloro-2-hydroxybenzoylamino)-5-hydroxymethyl-5,6-epoxy-2-cyclohexene-1,4-dione. Compound 2 was revealed to be the dechlorinated derivative of 1. Compounds 3 and 4 were determined to be the reduced derivative of 2 and 1, respectively.
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页码：912 / 915
页数：4
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