Breastfeeding and growth trajectory from birth to 5 years among children exposed and unexposed to gestational diabetes mellitus in utero

被引:3
作者
Dugas, Camille [1 ,2 ,3 ]
Kearney, Michele [1 ]
Perron, Julie [1 ]
Weisnagel, S. John [3 ]
Marc, Isabelle [4 ]
Robitaille, Julie [1 ,2 ,3 ]
机构
[1] Univ Laval, Inst Nutr & Funct Foods INAF, Ctr Rech Nutr Sante & Soc NUTRISS, Quebec City, PQ, Canada
[2] Univ Laval, Sch Nutr, Quebec City, PQ, Canada
[3] CHU Quebec Res Ctr, Endocrinol & Nephrol Axis, Quebec City, PQ, Canada
[4] Univ Laval, CHU Quebec Res Ctr, Dept Pediat, Quebec City, PQ, Canada
关键词
LONG-TERM IMPACT; BODY-COMPOSITION; FAT DISTRIBUTION; OBESITY RISK; WEIGHT-GAIN; CATCH-UP; CHILDHOOD; ADIPOSITY; ASSOCIATION; INFANCY;
D O I
10.1038/s41372-021-00932-y
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives This study aims to evaluate the association between exposure to gestational diabetes mellitus and growth trajectory from birth to 5 years and to test whether breastfeeding influences this association among children exposed and unexposed to gestational diabetes. Study design Weight at 0, 6, 12, and 18 months and 2, 3, 4, and 5 years were retrospectively collected for 103 children exposed and 63 children unexposed to gestational diabetes. Weight-for-age z-score was calculated. Mixed linear model for repeated measurements were computed to test whether breastfeeding was associated differently with weight-for-age z-score of children exposed or unexposed to diabetes. Results Children exposed to gestational diabetes had greater z-score values at 6 months and 4 and 5 years (p < 0.10). Breastfeeding duration was not associated with weight-for-age z-score trajectory in any children. Conclusion Children exposed to gestational diabetes had a different growth trajectory in early life, but breastfeeding duration did not seem to influence this association.
引用
收藏
页码:1033 / 1042
页数:10
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