Leukoplakia-A Diagnostic and Management Algorithm

被引:63
作者
Villa, Alessandro [1 ,2 ]
Woo, Sook Bin [1 ,2 ]
机构
[1] Harvard Sch Dent Med, Dept Oral Med Infect & Immun, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Div Oral Med & Dent, 1620 Tremont St,Suite BC 3-028, Boston, MA 02120 USA
关键词
PROLIFERATIVE VERRUCOUS LEUKOPLAKIA; POTENTIALLY MALIGNANT DISORDERS; SQUAMOUS-CELL CARCINOMAS; ORAL HAIRY LEUKOPLAKIA; EPSTEIN-BARR-VIRUS; BENIGN INTRAEPITHELIAL DYSKERATOSIS; WHITE SPONGE NEVUS; EPITHELIAL DYSPLASIA; PREMALIGNANT LESIONS; LICHEN-PLANUS;
D O I
10.1016/j.joms.2016.10.012
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Oral white lesions are frequently encountered in daily practice. Most white lesions are benign (eg, reactive keratoses or keratoses from inflammatory conditions) and the diagnosis is usually evident from the clinical presentation and histopathology. Leukoplakia is a common condition characterized by an increased risk for malignant transformation. Histopathology of leukoplakia can disclose hyperkeratosis with dysplasia or carcinoma or hyperkeratosis or parakeratosis without dysplasia. Treatment depends on demographic, social, clinical, and histopathologic factors. This review focuses on the diagnosis and management of oral leukoplakia. (C) 2016 American Association of Oral and Maxillofacial Surgeons
引用
收藏
页码:723 / 734
页数:12
相关论文
共 105 条
[1]   Optimal Management of Proliferative Verrucous Leukoplakia: A Systematic Review of the Literature [J].
Abadie, Wesley M. ;
Partington, Erin J. ;
Fowler, Craig B. ;
Schmalbach, Cecelia E. .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2015, 153 (04) :504-511
[2]   Oral candidiasis [J].
Akpan, A ;
Morgan, R .
POSTGRADUATE MEDICAL JOURNAL, 2002, 78 (922) :455-459
[3]   Oral lichen planus and oral lichenoid lesions:: diagnostic and therapeutic considerations [J].
Al-Hashimi, Ibtisam ;
Schifter, Mark ;
Lockhart, Peter B. ;
Wray, David ;
Brennan, Michael ;
Migliorati, Cesar A. ;
Axell, Tony ;
Bruce, Alison J. ;
Carpenter, William ;
Eisenberg, Ellen ;
Epstein, Joel B. ;
Holmstrup, Palle ;
Jontell, Mats ;
Lozada-Nur, Francina ;
Nair, Raj ;
Silverman, Bud ;
Thongprasom, Kobkan ;
Thornhill, Martin ;
Warnakulasuriya, Saman ;
van der Waal, Isaac .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2007, 103 (03) :S25-S31
[4]   Histopathological changes in oral mucosa due to takhzeen al-qat: a study of 70 biopsies [J].
Ali, AA ;
Al-Sharabi, AK ;
Aguirre, JM .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2006, 35 (02) :81-85
[5]   WHITE SPONGE NEVUS WITH EPIDERMOLYTIC CHANGES [J].
ALOI, FG ;
MOLINERO, A .
DERMATOLOGICA, 1988, 177 (05) :323-326
[6]  
Angiero F, 2008, ANTICANCER RES, V28, P2535
[7]   Proliferative verrucous leukoplakia: a concise update [J].
Bagan, J. ;
Scully, C. ;
Jimenez, Y. ;
Martorell, M. .
ORAL DISEASES, 2010, 16 (04) :328-332
[8]   Proliferative verrucous leukoplakia: high incidence of gingival squamous cell carcinoma [J].
Bagan, JV ;
Jimenez, Y ;
Sanchis, JM ;
Poveda, R ;
Milian, MA ;
Murillo, J ;
Scully, C .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2003, 32 (07) :379-382
[9]   Proliferative verrucous leukoplakia and its related lesions [J].
Batsakis, JG ;
Suarez, P ;
El-Naggar, AK .
ORAL ONCOLOGY, 1999, 35 (04) :354-359
[10]   Current and emerging treatment strategies for the treatment of actinic keratosis [J].
Berlin, Joshua M. .
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY, 2010, 3 :119-126