Catalyst- and chromatography-free synthesis of pyrrole-substituted indolinone derivatives in water

被引：6

作者：

Ahmad, Nazim A. A. ^{[1
]}

Rokade, Sunil M. ^{[1
]}

Garande, Ashok M. ^{[1
]}

Bhate, Prakash M. ^{[1
]}

机构：

[1] Inst Chem Technol, Dept Dyestuff Technol, Bombay 400019, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 40期

关键词：

3-(Pyrrol-1-yl)-indolin-2-one; Isatin; trans-4-Hydroxy-L-proline; Green chemistry; ONE-POT SYNTHESIS; THIAMINE HYDROCHLORIDE VB1; ORGANIC-REACTIONS; EFFICIENT PROMOTER; AQUEOUS-MEDIA; SOLVENT-FREE; CHEMISTRY; FOCUS;

D O I：

10.1016/j.tetlet.2014.08.001

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrrole-substituted indolinone derivatives were synthesized by the reaction of 4-hydroxyproline and isatin derivatives in water under catalyst-free conditions. The main advantages of this protocol besides the use of water as a solvent include short reaction time, practical simplicity, and high yield. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：5458 / 5461

页数：4

共 44 条

[1]

Ahluwalia V.K., 2009, GREEN SOLVENTS ORGAN

[2]

Anastas PT., 1998, GREEN CHEM FRONTIERS, DOI DOI 10.1021/JA995756G

[3] A novel one-pot synthesis of some new interesting pyrrole derivatives [J].

Azizian, J ;

Karimi, AR ;

Kazemizadeh, Z ;

Mohammadi, AA ;

Mohammadizadeh, MR .

JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (04) :1471-1473

[4] Homogeneous catalysis - Toward greener chemistry [J].

Baker, RT ;

Tumas, W .

SCIENCE, 1999, 284 (5419) :1477-1479

[5] Ultrasound-assisted bismuth nitrate-induced green synthesis of novel pyrrole derivatives and their biological evaluation as anticancer agents [J].

Bandyopadhyay, Debasish ;

Mukherjee, Sanghamitra ;

Granados, Jose C. ;

Short, John D. ;

Banik, Bimal K. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 50 :209-215

[6] Bismuth nitrate-catalyzed novel synthesis of pyrrole-substituted indolinones [J].

Banik, Bimal K. ;

Cardona, Magda .

TETRAHEDRON LETTERS, 2006, 47 (41) :7385-7387

[7] New pyrrole derivatives as antimycobacterial agents analogs of BM212 [J].

Biava, M ;

Fioravanti, R ;

Porretta, GC ;

Deidda, D ;

Maullu, C ;

Pompei, R .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (20) :2983-2988

[8] The leupyrrins:: A structurally unique family of secondary metabolites from the myxobacterium Sorangium cellulosum [J].

Bode, HB ;

Irschik, H ;

Wenzel, SC ;

Reichenbach, H ;

Müller, R ;

Höfle, G .

JOURNAL OF NATURAL PRODUCTS, 2003, 66 (09) :1203-1206

[9]

Bradley D., 1919, GREEN CHEM, V2010, P12

[10] Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents [J].

Carson, JR ;

Carmosin, RJ ;

Pitis, PM ;

Vaught, JL ;

Almond, HR ;

Stables, JP ;

Wolf, HH ;

Swinyard, EA ;

White, HS .

JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (11) :1578-1584

← 1 2 3 4 5 →