Diagnosis and Prognosis of Coronary Artery Disease with SPECT and PET

被引:34
作者
Al Badarin, Firas J. [1 ]
Malhotra, Saurabh [2 ,3 ]
机构
[1] St Lukes Mid Amer Heart Inst, Dept Cardiovasc Res, Kansas City, MO USA
[2] John H Stroger Jr Hosp Cook Cty, Cook Cty Hlth, Dept Cardiol, 1901 W Harrison St,Suite 3620, Chicago, IL 60612 USA
[3] Rush Med Coll, Dept Cardiol, Chicago, IL 60612 USA
基金
美国国家卫生研究院;
关键词
Myocardial perfusion imaging; Myocardial blood flow; Coronary artery disease; Diagnosis; Prognosis; POSITRON-EMISSION-TOMOGRAPHY; MYOCARDIAL BLOOD-FLOW; ISCHEMIC-HEART-DISEASE; CARDIOVASCULAR MAGNETIC-RESONANCE; APPROPRIATE USE CRITERIA; ACUTE CHEST-PAIN; COMPUTED-TOMOGRAPHY; RB-82; PET; EXERCISE ECHOCARDIOGRAPHY; VASCULAR DYSFUNCTION;
D O I
10.1007/s11886-019-1146-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of ReviewRadionuclide myocardial perfusion imaging (MPI) continues to be the most reliable modality for diagnosis of hemodynamically significant coronary artery disease (CAD). The application of radionuclide MPI using single photon emission computed tomography (SEPCT) and positron emission tomography (PET) for CAD is reviewed, with emphasis on diagnosis and risk stratification.Recent FindingsContemporary studies have reported the diagnostic and prognostic value of novel imaging protocols, employing stress-first or stress-only approach. In addition, the superior diagnostic value of PET has been established with a role of assessment of myocardial blood flow to improve risk stratification. The utility of MPI in special populations, such as the elderly, women, and diabetic patients has also been recently evaluated. Furthermore, multicenter studies have reported a similar diagnostic and prognostic value of radionuclide MPI compared with other functional and anatomical techniques for CAD.SummaryRadionuclide MPI with SPECT and PET are efficacious for diagnosis and prognosis of CAD. Its universal application in varied patient populations highlights its excellent clinical effectiveness.
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页数:11
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