The Neural Correlates of Planning and Executing Actual Tool Use

被引:112
作者
Brandi, Marie-Luise [1 ,2 ,3 ]
Wohlschlaeger, Afra [1 ,3 ]
Sorg, Christian [1 ,3 ]
Hermsdoerfer, Joachim [2 ]
机构
[1] Tech Univ Munich, Klinikum Rechts Isar, Neuroimaging Ctr, D-81675 Munich, Germany
[2] Tech Univ Munich, Inst Movement Sci, Dept Sports & Hlth Sci, D-80992 Munich, Germany
[3] Univ Munich, Grad Sch Syst Neurosci, D-82152 Planegg Martinsried, Germany
关键词
action execution; action planning; fMRI; tool use; POSTERIOR PARIETAL CORTEX; 2 ACTION SYSTEMS; CORTICAL NETWORKS; FUNCTIONAL MRI; ANTERIOR INTRAPARIETAL; CEREBRAL ASYMMETRIES; ADAPTATION REVEALS; PREMOTOR CORTICES; VENTRAL STREAM; USE PANTOMIMES;
D O I
10.1523/JNEUROSCI.0597-14.2014
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Human tool use is complex, and underlying neural mechanisms seem to be widely distributed across several brain systems; however, neuroimaging studies of actual tool use are rare because of experimental challenges hindering detailed analysis within one acting subject. Wedeveloped a "Tool-Carousel" that enabled us to test actual manipulation of different objects during fMRI and investigate the planning and execution of goal-directed actions. Particularly, we focused on the effects of three factors on object manipulations: the type of object manipulated, the type of manipulation, and the hand to be used. The main focus lay on the question of how complex object use compared with unspecific actions are processed and especially how such representations interact with the knowledge about the object in the action-related dorsal stream. We found that object manipulations with both right and left hand recruit a common network strongly lateralized to the left hemisphere especially during planning but also action execution. Specifically, while activity in the ventral stream was involved in processing semantic information and object properties, a dorso-dorsal pathway (i.e., superior occipital gyrus, superior parietal lobule, and dorsal premotor area) was relevant for monitoring the online control of objects and also a ventro-dorsal pathway (i.e., middle occipital gyrus, inferior parietal lobule, and ventral premotor area) was specifically involved in processing known object manipulations, such as tool use. Data further indicate an interaction of ventral stream areas, such as middle temporal gyrus and lateral occipital complex, with both dorsal pathways. These results provide evidence for left-lateralized occipito-temporo-parieto-frontal network of everyday tool use, which may help to characterize specific deficits in patients suffering from apraxia.
引用
收藏
页码:13183 / 13194
页数:12
相关论文
共 57 条
[1]   Parallel visual motion processing streams for manipulable objects and human movements [J].
Beauchamp, MS ;
Lee, KE ;
Haxby, JV ;
Martin, A .
NEURON, 2002, 34 (01) :149-159
[2]   Two action systems in the human brain [J].
Binkofski, Ferdinand ;
Buxbhaum, Laurel J. .
BRAIN AND LANGUAGE, 2013, 127 (02) :222-229
[3]   Distinctions between manipulation and function knowledge of objects: evidence from functional magnetic resonance imaging [J].
Boronat, CB ;
Buxbaum, LJ ;
Coslett, HB ;
Tang, K ;
Saffran, EM ;
Kimberg, DY ;
Detre, JA .
COGNITIVE BRAIN RESEARCH, 2005, 23 (2-3) :361-373
[4]   Action knowledge, visuomotor activation, and embodiment in the two action systems [J].
Buxbaum, Laurel J. ;
Kalenine, Solene .
YEAR IN COGNITIVE NEUROSCIENCE 2010, 2010, 1191 :201-218
[5]   Functional Magnetic Resonance Imaging Reveals the Neural Substrates of Arm Transport and Grip Formation in Reach-to-Grasp Actions in Humans [J].
Cavina-Pratesi, Cristiana ;
Monaco, Simona ;
Fattori, Patrizia ;
Galletti, Claudio ;
McAdam, Teresa D. ;
Quinlan, Derek J. ;
Goodale, Melvyn A. ;
Culham, Jody C. .
JOURNAL OF NEUROSCIENCE, 2010, 30 (31) :10306-10323
[6]   Functional magnetic resonance imaging during pantomiming tool-use gestures [J].
Choi, SH ;
Na, DL ;
Kang, E ;
Lee, KM ;
Lee, SW ;
Na, DG .
EXPERIMENTAL BRAIN RESEARCH, 2001, 139 (03) :311-317
[7]   Visually guided grasping produces fMRI activation in dorsal but not ventral stream brain areas [J].
Culham, JC ;
Danckert, SL ;
DeSouza, JFX ;
Gati, JS ;
Menon, RS ;
Goodale, MA .
EXPERIMENTAL BRAIN RESEARCH, 2003, 153 (02) :180-189
[8]   A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data [J].
Eickhoff, SB ;
Stephan, KE ;
Mohlberg, H ;
Grefkes, C ;
Fink, GR ;
Amunts, K ;
Zilles, K .
NEUROIMAGE, 2005, 25 (04) :1325-1335
[9]   Tool use, communicative gesture and cerebral asymmetries in the modern human brain [J].
Frey, Scott H. .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2008, 363 (1499) :1951-1957
[10]   Decoding the neural mechanisms of human tool use [J].
Gallivan, Jason P. ;
McLean, D. Adam ;
Valyear, Kenneth F. ;
Culham, Jody C. .
ELIFE, 2013, 2