Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli

被引：9

作者：

Ahn, Kwangjin ^{[1
]}

Hwang, Gyu Yel ^{[1
]}

Kim, Young Keun ^{[2
,3
]}

Kim, Hyo Youl ^{[2
,3
]}

Jeong, Hye Ran ^{[3
]}

Hong, Jun Sung ^{[4
,5
]}

Uh, Young ^{[1
,3
]}

机构：

[1] Yonsei Univ, Wonju Coll Med, Wonju Severance Christian Hosp, Dept Lab Med, Wonju, South Korea

[2] Yonsei Univ, Wonju Coll Med, Wonju Severance Christian Hosp, Dept Internal Med, Wonju, South Korea

[3] Yonsei Univ, Wonju Coll Med, Wonju Severance Christian Hosp, Infect Control Dept, Wonju, South Korea

[4] Yonsei Univ, Coll Med, Dept Lab Med, Seoul, South Korea

[5] Yonsei Univ, Coll Med, Res Inst Antimicrobial Resistance, Seoul, South Korea

来源：

INFECTION AND CHEMOTHERAPY | 2019年 / 51卷 / 02期

关键词：

New Delhi metallo-enzyme carbapenemase; Oxacillin-hydrolyzing beta-lactamase; Escherichia coli; Carbapenemase-producing Enterobacteriaceae; Outbreak control; OXA-48; CARRIAGE;

D O I：

10.3947/ic.2019.51.2.177

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced bla(NDM-5) and bla(OXA-181) carbapenemase genes and shared >= 88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.

引用

页码：177 / 182

页数：6

共 14 条

[1]

[Anonymous], LAB PROT DET CARB RE

[2] Prevalence of Extended-Spectrum Beta-Lactamase and Carbapenemase Genes in Clinical Isolates of Escherichia coli in Myanmar: Dominance of blaNDM-5 and Emergence of blaOXA-181 [J].

Aung, Meiji Soe ;

San, Nilar ;

Maw, Win Win ;

San, Thida ;

Urushibara, Noriko ;

Kawaguchiya, Mitsuyo ;

Sumi, Ayako ;

Kobayashi, Nobumichi .

MICROBIAL DRUG RESISTANCE, 2018, 24 (09) :1333-1344

[3]

Centers for Disease Control and Prevention, FAC GUID CONTR CARB

[4] Klebsiella pneumoniae Co-Producing NDM-5 and OXA-181 Carbapenemases, South Korea [J].

Cho, Sun Young ;

Huh, Hee Jae ;

Baek, Jin Yang ;

Chung, Na Yeon ;

Ryu, Jae Geum ;

Ki, Chang-Seok ;

Chung, Doo Ryeon ;

Lee, Nam Yong ;

Song, Jae-Hoon .

EMERGING INFECTIOUS DISEASES, 2015, 21 (06) :1088-1089

[5] NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman [J].

Dortet, L. ;

Poirel, L. ;

Al Yaqoubi, F. ;

Nordmann, P. .

CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (05) :E144-E148

[6] New Delhi Metallo-β-Lactamase-Producing Carbapenem-Resistant Escherichia coli Associated With Exposure to Duodenoscopes [J].

Epstein, Lauren ;

Hunter, Jennifer C. ;

Arwady, M. Allison ;

Tsai, Victoria ;

Stein, Linda ;

Gribogiannis, Marguerite ;

Frias, Mabel ;

Guh, Alice Y. ;

Laufer, Alison S. ;

Black, Stephanie ;

Pacilli, Massimo ;

Moulton-Meissner, Heather ;

Rasheed, J. Kamile ;

Avillan, Johannetsy J. ;

Kitchel, Brandon ;

Limbago, Brandi M. ;

MacCannell, Duncan ;

Lonsway, David ;

Noble-Wang, Judith ;

Conway, Judith ;

Conover, Craig ;

Vernon, Michael ;

Kallen, Alexander J. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2014, 312 (14) :1447-1455

[7] Control of carbapenemase-producing Enterobacteriaceae outbreaks in acute settings: an evidence review [J].

French, C. E. ;

Coope, C. ;

Conway, L. ;

Higgins, J. P. T. ;

McCulloch, J. ;

Okoli, G. ;

Patel, B. C. ;

Oliver, I. .

JOURNAL OF HOSPITAL INFECTION, 2017, 95 (01) :3-45

[8] NDM-5 and OXA-48 Co-producing Uropathogenic Escherichia coli Isolate: First Case in Korea [J].

Jhang, Jinho ;

Wang, Hye-young ;

Yoo, Gilsung ;

Hwang, Gyu Yel ;

Uh, Young ;

Yoon, Kap Jun .

ANNALS OF LABORATORY MEDICINE, 2018, 38 (03) :277-279

[9] Long-Term Carriage of Vancomycin-Resistant Enterococci in Patients Discharged from Hospitals: a 12-Year Retrospective Cohort Study [J].

Karki, Surendra ;

Land, Gillian ;

Aitchison, Stacey ;

Kennon, Jacqueline ;

Johnson, Paul D. R. ;

Ballard, Susan A. ;

Leder, Karin ;

Cheng, Allen C. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (10) :3374-3379

[10] Emergence of Escherichia coli, Co-Producing NDM-1 and OXA-48 Carbapenemases, in Urinary Isolates, at a Tertiary Care Centre at Central India [J].

Khajuria, Atul ;

Praharaj, Ashok Kumar ;

Kumar, Mahadevan ;

Grover, Naveen .

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2014, 8 (06) :DC1-DC4

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