Anti-hypertensive Nutraceuticals and Functional Foods

被引:159
作者
Chen, Zhen-Yu [1 ]
Peng, Cheng [1 ]
Jiao, Rui [1 ]
Wong, Yin Mei [1 ]
Yang, Nan [1 ]
Huang, Yu [2 ]
机构
[1] Chinese Univ Hong Kong, Food & Nutr Sci Programme, Dept Biochem, Shatin, Hong Kong, Peoples R China
[2] Chinese Univ Hong Kong, Dept Physiol, Shatin, Hong Kong, Peoples R China
关键词
ACE; chlorogenic acid; eNOS; fermented milk; fish oil; garlic; ginger; hawthorn; hypertension; L-arginine; onion; tea; GINKGO-BILOBA EXTRACT; ENZYME-INHIBITORY-ACTIVITY; LOWERS BLOOD-PRESSURE; LONG-TERM INTAKE; SPONTANEOUSLY HYPERTENSIVE-RATS; L-ARGININE SUPPLEMENTATION; FATTY-ACID SUPPLEMENTS; GARLIC ALLIUM-SATIVUM; COFFEE BEAN EXTRACT; DIETARY FISH-OIL;
D O I
10.1021/jf900803r
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
Epidemiological studies have demonstrated that elevated blood pressure is one of the major risk factors for stroke and coronary heart disease (CHID). A close association between blood pressure and the incidence of cardiovascular diseases is well established if systolic/diastolic blood pressure is above 140/90 mmHg. In recent years, nutraceuticals and functional foods have attracted considerable interest as potential alternative therapies for treatment of hypertension, especially for prehypertensive patients, whose blood pressure is marginally or mildly high but not high enough to warrant the prescription of blood pressure-lowering medications. This review summarizes the findings of recent studies on the chemistry, production, application, efficacy, and mechanisms of popular blood pressure-lowering nutraceuticals and functional foods including the Dietary Approaches to Stop Hypertension (DASH) diet plan, L-arginine, chlorogenic acid, fermented milk, garlic, onion, tea, soybean, ginger, hawthorn, and fish oil.
引用
收藏
页码:4485 / 4499
页数:15
相关论文
共 156 条
  • [1] DAIRY-PRODUCTS, CALCIUM, AND BLOOD-PRESSURE
    ACKLEY, S
    BARRETTCONNOR, E
    SUAREZ, L
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1983, 38 (03) : 457 - 461
  • [2] Effects of long-term intake of edible oils on hypertension and myocardial and aortic remodelling in spontaneously hypertensive rats
    Aguila, MB
    Silva, SPS
    Pinheiro, AR
    Mandarim-De-Lacerda, CA
    [J]. JOURNAL OF HYPERTENSION, 2004, 22 (05) : 921 - 929
  • [3] Neuroprotective effects of Ginkgo biloba extract
    Ahlemeyer, B
    Krieglstein, J
    [J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2003, 60 (09) : 1779 - 1792
  • [4] Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension
    Aihara, K
    Kajimoto, O
    Hirata, H
    Takahashi, R
    Nakamura, Y
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2005, 24 (04) : 257 - 265
  • [5] AKIKO O, 1995, PLANT FOOD HUM NUTR, V47, P39
  • [6] Thromboxane-B2, prostaglandin-E2 and hypertension in the rat 2-kidney 1-clip model: a possible mechanism of the garlic induced hypotension
    Al-Qattan, KK
    Khan, I
    Alnaqeeb, MA
    Ali, M
    [J]. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2001, 64 (01): : 5 - 10
  • [7] The antihypertensive effect of garlic (Allium sativum) in the rat two-kidney-one-clip Goldblatt model
    Al-Qattan, KK
    Alnaqeeb, MA
    Ali, M
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 1999, 66 (02) : 217 - 222
  • [8] Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research
    Ali, Badreldin H.
    Blunden, Gerald
    Tanira, Musbah O.
    Nemmar, Abderrahim
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2008, 46 (02) : 409 - 420
  • [9] Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet
    Ali, M
    Al-Qattan, KK
    Al-Enezi, F
    Khanafer, RMA
    Mustafa, T
    [J]. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2000, 62 (04): : 253 - 259
  • [10] Effects of oral L-arginine supplementation on blood pressure and asymmetric dimethylarginine in stress-induced preeclamptic rats
    Altun, Zekiye Sultan
    Uysal, Sezer
    Guner, Gul
    Yilmaz, Osman
    Posaci, Cemal
    [J]. CELL BIOCHEMISTRY AND FUNCTION, 2008, 26 (05) : 648 - 653