Enantioselective Intramolecular C-H Insertion Reactions of Donor Donor Metal Carbenoids

被引：124

作者：

Soldi, Cristian ^{[1
]}

Lamb, Kellan N. ^{[1
]}

Squitieri, Richard A. ^{[1
]}

Gonzalez-Lopez, Marcos ^{[1
]}

Di Maso, Michael J. ^{[1
]}

Shaw, Jared T. ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 136卷 / 43期

关键词：

CATALYZED DECOMPOSITION; ORGANIC-SYNTHESIS; DIAZO-COMPOUNDS; TOSYLHYDRAZONES; BONDS; DIRHODIUM(II); HOPEAHAINOL; DERIVATIVES; COMPLEXES; SULFONES;

D O I：

10.1021/ja508586t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first asymmetric insertion reactions of donor-donor carbenoids, i.e., those with no pendant electron-withdrawing groups, are reported. This process enables the synthesis of densely substituted benzodihydrofurans with high levels of enantio- and diastereoselectivity. Preliminary results show similar efficiency in the preparation of indanes. This new method is used in the first enantioselective synthesis of an oligoresveratrol natural product (E-delta-viniferin).

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收藏

页码：15142 / 15145

页数：4

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