Nosocomial infection with vancomycin-dependent enterococci

被引：23

作者：

Tambyah, PA ^{[1
]}

Marx, JA ^{[1
]}

Maki, DG ^{[1
]}

机构：

[1] Univ Wisconsin, Sch Med, Madison, WI USA

来源：

EMERGING INFECTIOUS DISEASES | 2004年 / 10卷 / 07期

关键词：

D O I：

10.3201/eid1007.030993

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report three patients infected with unique strains of vancomycin-dependent enterococci. Two were first infected by genetically identical strains of vancomycin-resistant enterococci (VRE). All three patients had much greater exposure to vancomycin and third-generation cephalosporins than did two control groups (patients infected with VRE and hospitalized patients without enterococcal infections). While antimicrobial pressure promotes nosocomial colonization by VRE, prolonged exposure to vancomycin may foster the transition from vancomycin resistance to dependence.

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页码：1277 / 1281

页数：5

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