Twelfth Cranial Nerve Involvement in Guillain-Barre Syndrome: A Case Report

Guillain-Barre syndrome (GBS) is a common neurologic disease with paresthesia, albuminocytologic dissociation in cerebrospinal fluid analysis, accompanied by motor weakness, areflexia/hyporeflexia and mild sensory loss. Cranial nerve involvement is seen in 45-75% of patients with GBS. Of all cranial nerves, the 12th cranial nerve is the most rarely involved nerve and very few cases have been described in the literature. This case is presented because it is an atypical case with hypoglossal nerve involvement, as well as significant asymmetric impairment of the upper extremities.