Supramolecular Polymers in Aqueous Media

被引:620
作者
Krieg, Elisha [1 ,2 ,3 ]
Bastings, Maartje M. C. [1 ,2 ,3 ]
Besenius, Pol [4 ]
Rybtchinski, Boris [5 ]
机构
[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
[2] Harvard Univ, Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA
[3] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA
[4] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany
[5] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel
基金
以色列科学基金会;
关键词
HELICAL ROSETTE NANOTUBES; PERYLENE BISIMIDE DYES; TOBACCO-MOSAIC-VIRUS; THERMORESPONSIVE CYCLIC PEPTIDE; HYBRIDIZATION CHAIN-REACTION; HEXA-PERI-HEXABENZOCORONENE; GLUTATHIONE-S-TRANSFERASE; SELF-ASSEMBLED STRUCTURES; ARTIFICIAL BETA-BARRELS; DNA NANOTUBES;
D O I
10.1021/acs.chemrev.5b00369
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review discusses one-dimensional supramolecular polymers that form in aqueous media. First, naturally occurring supramolecular polymers are described, in particular, amyloid fibrils, actin filaments, and microtubules. Their structural, thermodynamic, kinetic, and nanomechanical properties are highlighted, as well as their importance for the advancement of biologically inspired supramolecular polymer materials. Second, five classes of synthetic supramolecular polymers are described: systems based on (1) hydrogen-bond motifs, (2) large pi-conjugated surfaces, (3) host guest interactions, (4) peptides, and (5) DNA. We focus on recent studies that address key challenges in the field, providing mechanistic understanding, rational polymer design, important functionality, robustness, or unusual thermodynamic and kinetic properties.
引用
收藏
页码:2414 / 2477
页数:64
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