Recent advances of traditional Chinese medicine on the prevention and treatment of COVID-19

被引：77

作者：

Dai Yu-Jie ^{[1
]}

Wan Shi-Yao ^{[1
]}

Gong Shuai-Shuai ^{[1
]}

Liu Jin-Cheng ^{[1
]}

Li Fang ^{[1
]}

Kou Jun-Ping ^{[1
]}

机构：

[1] China Pharmaceut Univ, Sch Tradit Chinese Pharm, Dept Pharmacol Chinese Mat Med, Jiangsu Key Lab TCM Evaluat & Translat Res, Nanjing 211198, Peoples R China

来源：

CHINESE JOURNAL OF NATURAL MEDICINES | 2020年 / 18卷 / 12期

关键词：

Novel coronavirus pneumonia; Prescription of traditional Chinese medicine; Single Chinese herb; Active ingredients of traditional Chinese medicine; Viral infection; CORONAVIRUS DISEASE 2019; NETWORK PHARMACOLOGY; MECHANISM; INJECTION;

D O I：

10.1016/S1875-5364(20)60031-0

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Coronavirus disease-2019 (COVID-19) is a new highly infectious disease caused by a novel coronavirus. Recently, the number of new cases infected pneumonia in the world continues to increase, which has aroused great concern from the international community. At present, there are no small-molecule specific anti-viral drugs for the treatment. The high mortality rate seriously threatens human health. Traditional Chinese medicine (TCM) is a unique health resource in China. The combination of TCM and Western medicine has played a positive and important role in combating COVID-19 in China. In this review, through literature mining and analysis, it was found that TCM has the potential to prevent and treat the COVID-19. Then, the network pharmacological studies demonstrated that TCM played roles of anti-virus, anti-inflammation and immunoregulation in the management of COVID-19 via multiple components acting on multiple targets and multiple pathways. Finally, clinical researches also confirmed the beneficial effects of TCM on the treatment of patients. This review may provide meaningful and useful information on further drug development of COVID-19 and other viral infectious diseases.

引用

页码：881 / 889

页数：9

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