Polycycloiridals A-D, Four Iridal-Type Triterpenoids with an α-Terpineol Moiety from Iris tectorum

被引：36
|
作者：
Zhang, Chun-Lei [1 ,2 ,3 ]
Liu, Yan-Fei [1 ,2 ]
Wang, Yan [1 ,2 ]
Liang, Dong [1 ,2 ]
Jiang, Zhi-Bo [1 ,2 ]
Li, Li [1 ,2 ]
Hao, Zhi-You [1 ,2 ]
Luo, Huan [1 ,2 ]
Shi, Guo-Ru [1 ,2 ]
Chen, Ruo-Yun [1 ,2 ]
Cao, Zheng-Yu [3 ]
Yu, De-Quan [1 ,2 ]
机构：
[1] Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China
[2] Peking Union Med Coll, Beijing 100050, Peoples R China
[3] China Pharmaceut Univ, Sch TCM, Jiangsu Prov Key Lab TCM Evaluat & Translat Dev, Nanjing 211198, Jiangsu, Peoples R China
来源：
ORGANIC LETTERS | 2015年 / 17卷 / 22期
关键词：
D O I：
10.1021/acs.orglett.5b02982
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Polycycloiridals AD, four novel iridals with an unprecedented alpha-terpineol moiety resulting from cyclization of the homofarnesylside chain, were isolated from the ethanol extract of rhizomes of Iris tectorum. Their structures were elucidated on the basis of comprehensive spectroscopic analysis. The absolute configuration of 1 was determined by the modified Moshers method and comparison of experimental and calculated electronic circular dichroism (ECD) spectrum. A possible biosynthetic pathway was postulated.
引用
收藏
页码：5686 / 5689
页数：4
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