H-NS gives invading DNA the silent treatment

被引：4

作者：

Pflum, Mary Kay H. ^{[1
]}

机构：

[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA

来源：

NATURE CHEMICAL BIOLOGY | 2006年 / 2卷 / 08期

关键词：

D O I：

10.1038/nchembio0806-400

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Though uptake of beneficial foreign DNA confers fitness advantages to bacteria, the mechanisms protecting bacteria from harmful foreign DNA have been unclear. A new study suggests that the H-NS protein transcriptionally silences invading DNA by recognizing its low G-C content, thereby protecting cell viability during bacterial evolution.

引用

页码：400 / 401

页数：3

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