Evidence of Henipavirus Infection in West African Fruit Bats

被引：171

作者：

Hayman, David T. S. ^{[1
,2
]}

Suu-Ire, Richard ^{[3
]}

Breed, Andrew C. ^{[4
,5
]}

McEachern, Jennifer A. ^{[5
,6
]}

Wang, Linfa ^{[5
,6
]}

Wood, James L. N. ^{[2
]}

Cunningham, Andrew A. ^{[1
]}

机构：

[1] Zool Soc London, Inst Zool, London NW1 4RY, England

[2] Univ Cambridge, Cambridge Infect Dis Consortium, Cambridge, England

[3] Wildlife Div Forestry Commission, Accra, Ghana

[4] Univ Queensland, Sch Vet Sci, Brisbane, Qld, Australia

[5] Australian Biosecurity Cooperat Res Ctr, Geelong, Vic, Australia

[6] Australian Anim Hlth Lab, CSIRO Livestock Industries, Geelong, Vic, Australia

来源：

PLOS ONE | 2008年 / 3卷 / 07期

关键词：

D O I：

10.1371/journal.pone.0002739

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27-51%) and Hendra (22%, 95% CI: 11-33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa.

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页数：4

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