FRET based 'red-switch' for Al3+ over ESIPT based 'green-switch' for Zn2+: dual channel detection with live-cell imaging on a dyad platform

被引:121
作者
Goswami, Shyamaprosad [1 ]
Manna, Abhishek [1 ]
Paul, Sima [1 ]
Maity, Anup Kumar [2 ]
Saha, Partha [2 ]
Quah, Ching Kheng [3 ]
Fun, Hoong-Kun [3 ,4 ]
机构
[1] Indian Inst Engn Sci & Technol, Dept Chem, Sibpur, W Bengal, India
[2] Saha Inst Nucl Phys, Crystallog & Mol Biol Div, Kolkata, W Bengal, India
[3] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George Town, Malaysia
[4] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia
关键词
SELECTIVE FLUORESCENCE DETECTION; AQUEOUS-MEDIA; RATIOMETRIC DETECTION; ALZHEIMERS-DISEASE; SCHIFF-BASE; SENSOR; CHEMOSENSOR; ALUMINUM; PROBE; IONS;
D O I
10.1039/c4ra05714g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Our designed chemosensor, rhodamine-HBT-dyad (RHD), selectively detects two biologically important ions (Al3+ and Zn2+) at two different wavelengths ('naked-eye' colors red and green, respectively) through two different mechanisms (i.e. FRET and ESIPT) at ppm level. The sensor can also detect the Al3+ ion through displacement of the Zn2+ ion in vivo.
引用
收藏
页码:34572 / 34576
页数:5
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