Risks of nutrigenomics and nutrigenetics? What the scientists say

被引:15
作者
Hurlimann, T. [1 ,2 ]
Menuz, V. [2 ]
Graham, J. [2 ,3 ]
Robitaille, J. [2 ,4 ]
Vohl, M-C [2 ,4 ]
Godard, B. [1 ,2 ]
机构
[1] Univ Montreal, Sch Publ Hlth ESPUM, Dept Social & Prevent Med, Bioeth Programmes, Montreal, PQ H3C 3J7, Canada
[2] Univ Montreal, Om Eth Res Grp, Montreal, PQ H3C 3J7, Canada
[3] Dalhousie Univ, Dept Pediat, TRRU, Halifax, NS, Canada
[4] Univ Laval, Inst Nutr & Funct Foods INAF, Dept Food Sci & Nutr, Quebec City, PQ, Canada
基金
加拿大健康研究院;
关键词
Nutrigenomics; Ethics; Risks; Benefits; Researchers; Survey; CONSUMER GENETIC TESTS; PERSONALIZED NUTRITION; HEALTH DISPARITIES; CLINICAL-RESEARCH; GENOMICS; ETHICS; FOOD; MEDICINE; INTERVENTION; INDIVIDUALS;
D O I
10.1007/s12263-013-0370-6
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioethical considerations that challenge NGx implementation. This paper focuses on the opinions of NGx researchers about potential risks raised by NGx. The results of an online survey show that these researchers (n = 126) are fairly confident about the potential benefits of NGx, and that most downplay its potential risks. Researchers in this field do not believe that NGx will reconfigure foods as medication or transform the conception of eating into a health hazard. The majority think that NGx will produce no added burden on individuals to get tested or to remain compliant with NGx recommendations, nor that NGx will threaten individual autonomy in daily food choice. The majority of researchers do not think that NGx will lead to discrimination against and/or stigmatization of people who do not comply with NGx dietary recommendations. Despite this optimism among NGx researchers, we suggest that key risk factors raised by the socioethical context in which NGx applications will be implemented need to be considered.
引用
收藏
页数:12
相关论文
共 86 条
[71]   Biomarkers of Nutrient Bioactivity and Efficacy A Route Toward Personalized Nutrition [J].
Rubio-Aliaga, Isabel ;
Kochhar, Sunil ;
Silva-Zolezzi, Irma .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2012, 46 (07) :545-554
[72]   Increasing Public Awareness of Direct-to-Consumer Genetic Tests: Health Care Access, Internet Use, and Population Density Correlates [J].
Rutten, Lila J. Finney ;
Gollust, Sarah E. ;
Naveed, Sana ;
Moser, Richard P. .
JOURNAL OF CANCER EPIDEMIOLOGY, 2012, 2012
[73]   State of play in direct-to-consumer genetic testing for lifestyle-related diseases: market, marketing content, user experiences and regulation [J].
Saukko, Paula .
PROCEEDINGS OF THE NUTRITION SOCIETY, 2013, 72 (01) :53-60
[74]   Personalised Medicine: A Critique on the Future of Health Care [J].
Savard, Jacqueline .
JOURNAL OF BIOETHICAL INQUIRY, 2013, 10 (02) :197-203
[75]   Re-imagining the 'social' in the nutrition sciences [J].
Schubert, Lisa ;
Gallegos, Danielle ;
Foley, Wendy ;
Harrison, Claire .
PUBLIC HEALTH NUTRITION, 2012, 15 (02) :352-359
[76]   "Snake-oil," "quack medicine," and "industrially cultured organisms:" biovalue and the commercialization of human microbiome research [J].
Slashinski, Melody J. ;
McCurdy, Sheryl A. ;
Achenbaum, Laura S. ;
Whitney, Simon N. ;
McGuire, Amy L. .
BMC MEDICAL ETHICS, 2012, 13
[77]   Benefits Associated with Nutrigenomics Research and Their Reporting in the Scientific Literature: Researchers' Perspectives [J].
Stenne, R. ;
Hurlimann, T. ;
Godard, B. .
ACCOUNTABILITY IN RESEARCH-POLICIES AND QUALITY ASSURANCE, 2013, 20 (03) :167-183
[78]   Are Research Papers Reporting Results from Nutrigenetics Clinical Research a Potential Source of Biohype? [J].
Stenne, R. ;
Hurlimann, T. ;
Godard, Beatrice .
ACCOUNTABILITY IN RESEARCH-POLICIES AND QUALITY ASSURANCE, 2012, 19 (05) :285-307
[79]   Cancer and diet: How are they related? [J].
Sung, Bokyung ;
Prasad, Sahdeo ;
Yadav, Vivek R. ;
Lavasanifar, Afsaneh ;
Aggarwal, Bharat B. .
FREE RADICAL RESEARCH, 2011, 45 (08) :864-879
[80]   Nature or nurture: Let food be your epigenetic medicine in chronic inflammatory disorders [J].
Szic, Katarzyna Szarc Vel ;
Ndlovu, Matladi N. ;
Haegeman, Guy ;
Vanden Berghe, Wim .
BIOCHEMICAL PHARMACOLOGY, 2010, 80 (12) :1816-1832