Risks of nutrigenomics and nutrigenetics? What the scientists say

被引:15
作者
Hurlimann, T. [1 ,2 ]
Menuz, V. [2 ]
Graham, J. [2 ,3 ]
Robitaille, J. [2 ,4 ]
Vohl, M-C [2 ,4 ]
Godard, B. [1 ,2 ]
机构
[1] Univ Montreal, Sch Publ Hlth ESPUM, Dept Social & Prevent Med, Bioeth Programmes, Montreal, PQ H3C 3J7, Canada
[2] Univ Montreal, Om Eth Res Grp, Montreal, PQ H3C 3J7, Canada
[3] Dalhousie Univ, Dept Pediat, TRRU, Halifax, NS, Canada
[4] Univ Laval, Inst Nutr & Funct Foods INAF, Dept Food Sci & Nutr, Quebec City, PQ, Canada
基金
加拿大健康研究院;
关键词
Nutrigenomics; Ethics; Risks; Benefits; Researchers; Survey; CONSUMER GENETIC TESTS; PERSONALIZED NUTRITION; HEALTH DISPARITIES; CLINICAL-RESEARCH; GENOMICS; ETHICS; FOOD; MEDICINE; INTERVENTION; INDIVIDUALS;
D O I
10.1007/s12263-013-0370-6
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioethical considerations that challenge NGx implementation. This paper focuses on the opinions of NGx researchers about potential risks raised by NGx. The results of an online survey show that these researchers (n = 126) are fairly confident about the potential benefits of NGx, and that most downplay its potential risks. Researchers in this field do not believe that NGx will reconfigure foods as medication or transform the conception of eating into a health hazard. The majority think that NGx will produce no added burden on individuals to get tested or to remain compliant with NGx recommendations, nor that NGx will threaten individual autonomy in daily food choice. The majority of researchers do not think that NGx will lead to discrimination against and/or stigmatization of people who do not comply with NGx dietary recommendations. Despite this optimism among NGx researchers, we suggest that key risk factors raised by the socioethical context in which NGx applications will be implemented need to be considered.
引用
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页数:12
相关论文
共 86 条
[1]   Nutrigenomics:: From molecular nutrition to prevention of disease [J].
Afman, L ;
Müller, M .
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 2006, 106 (04) :569-576
[2]   Molecular targets of dietary agents for prevention and therapy of cancer [J].
Aggarwal, BB ;
Shishodia, S .
BIOCHEMICAL PHARMACOLOGY, 2006, 71 (10) :1397-1421
[3]  
[Anonymous], GETT PERS SHIFT RESP
[4]   Direct-to-Consumer Personal Genome Testing and Cancer Risk Prediction [J].
Bellcross, Cecelia A. ;
Page, Patricia Z. ;
Meaney-Delman, Dana .
CANCER JOURNAL, 2012, 18 (04) :293-302
[5]   Bioethical considerations for human nutrigenomics [J].
Bergmann, Manuela M. ;
Goerman, Ulf ;
Mathers, John C. .
ANNUAL REVIEW OF NUTRITION, 2008, 28 :447-467
[6]   How People Interpret Healthy Eating: Contributions of Qualitative Research [J].
Bisogni, Carole A. ;
Jastran, Margaret ;
Seligson, Marc ;
Thompson, Alyssa .
JOURNAL OF NUTRITION EDUCATION AND BEHAVIOR, 2012, 44 (04) :282-301
[7]  
Blair Jennifer, 2012, Minn Med, V95, P45
[8]   Direct-to-consumer personalized genomic testing [J].
Bloss, Cinnamon S. ;
Darst, Burcu F. ;
Topol, Eric J. ;
Schork, Nicholas J. .
HUMAN MOLECULAR GENETICS, 2011, 20 :R132-R141
[9]  
Brand Angela, 2012, Drug Metabolism and Drug Interactions, V27, P121, DOI 10.1515/dmdi-2012-0028
[10]   Public Health Genomics - public health goes personalized? [J].
Brand, Angela .
EUROPEAN JOURNAL OF PUBLIC HEALTH, 2011, 21 (01) :2-3