High Incidence of Escherichia coli Strains Coharboring mcr-1 and blaNDM from Chickens

被引：3
作者：
Liu, Bao-Tao [1 ,3 ]
Song, Feng-Jing [2 ]
Zou, Ming [1 ]
Zhang, Qi-Di [1 ]
Shan, Hu [1 ,3 ]
机构：
[1] Qingdao Agr Univ, Coll Anim Sci & Vet Med, Qingdao, Peoples R China
[2] Qingdao Acad Agr Sci, Qingdao, Peoples R China
[3] Qingdao Agr Univ, Engn Technol Res Ctr Vet Med & Diagnost Reagents, Qingdao, Peoples R China
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2017年 / 61卷 / 03期
基金：
中国国家自然科学基金;
关键词：
high incidence; mcr-1; bla(NDM); colocalization; Escherichia coli; SPECTRUM-BETA-LACTAMASE; RESISTANCE GENE MCR-1; KLEBSIELLA-PNEUMONIAE; CARBAPENEM-RESISTANT; PLASMID; ENTEROBACTERIACEAE; IDENTIFICATION; EMERGENCE; CHINA; DISSEMINATION;
D O I：
10.1128/AAC.02347-16
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This study investigated the characteristics of Escherichia coli isolates carrying mcr-1-bla(NDM) from a chicken farm in China. Of the 78 E. coli isolates, 21 clonally unrelated isolates carried mcr-1-bla(NDM). Diverse IncI2 plasmids disseminated mcr-1, while the dissemination of blaNDM was mediated by diverse IncB/O plasmids. More striking was the colocalization of resistance genes mcr-1 and blaNDM-4 in an IncHI2/ST3 plasmid, which might pose a great challenge for public health.
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页数：7
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