Metabolic Syndrome

被引：489

作者：

Samson, Susan L. ^{[1
]}

Garber, Alan J. ^{[1
,2
,3
]}

机构：

[1] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Biochem & Mol Biol, Houston, TX 77030 USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2014年 / 43卷 / 01期

关键词：

Metabolic syndrome; Obesity; Dyslipidemia; Hypertension; Cardiovascular risk; Diabetes risk; National Cholesterol Education Program Adult Treatment Panel III; CORONARY-HEART-DISEASE; FATTY LIVER-DISEASE; NUTRITION EXAMINATION SURVEY; DIABETES PREVENTION PROGRAM; POLYCYSTIC-OVARY-SYNDROME; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; ADIPOSE-TISSUE; RISK-FACTORS; NATIONAL-HEALTH;

D O I：

10.1016/j.ecl.2013.09.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Metabolic syndrome is not a disease per se, but is a term that highlights traits that may have an increased risk of disease, approximately 2-fold for cardiovascular disease and 5-fold or more for type 2 diabetes mellitus. Obesity and insulin resistance are believed to be at the core of most cases of metabolic syndrome, although further research is required to truly understand the pathophysiology behind the syndrome and the gene-environment interactions that increase susceptibility. The mainstay of treatment remains lifestyle changes with exercise and diet to induce weight loss and pharmacologic intervention to treat atherogenic dyslipidemia, hypertension, and hyperglycemia.

引用

页码：1 / +

页数：24

共 128 条

[1] Metabolic syndrome - a new world-wide definition. A consensus statement from the international diabetes federation
Alberti, KGMM
Zimmet, P
Shaw, J
[J]. DIABETIC MEDICINE, 2006, 23 (05) : 469 - 480
[2] Alberti KGMM, 1998, DIABETIC MED, V15, P539, DOI 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO
[3] 2-S
[4] Metabolic syndrome and population attributable risk among HIV/AIDS patients: comparison between NCEP-ATPIII, IDF and AHA/NHLBI definitions
Alencastro, Paulo R.
Wolff, Fernando H.
Oliveira, Renato R.
Ikeda, Maria Leticia R.
Barcellos, Nemora T.
Brandao, Ajacio B. M.
Fuchs, Sandra C.
[J]. AIDS RESEARCH AND THERAPY, 2012, 9
[5] Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction
Andreassi, Maria Grazia
[J]. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2009, 667 (1-2) : 35 - 43
[6] [Anonymous], 1975, JAMA-J AM MED ASSOC, V231, P360
[7] Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
Apridonidze, T
Essah, PA
Iuorno, MJ
Nestler, JE
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (04) : 1929 - 1935
[8] Prevalence of Metabolic Syndrome in Adult Hypopituitary Growth Hormone (GH)-Deficient Patients Before and After GH Replacement
Attanasio, Andrea F.
Mo, Daojun
Erfurth, Eva Marie
Tan, Meng
Ho, Ken Y.
Kleinberg, David
Zimmermann, Alan G.
Chanson, Philippe
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (01) : 74 - 81
[9] Balkau B, 1999, DIABETIC MED, V16, P442
[10] Prevalence and Trends of Metabolic Syndrome in the Adult U.S. Population, 1999-2010
Beltran-Sanchez, Hiram
Harhay, Michael O.
Harhay, Meera M.
McElligott, Sean
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 62 (08) : 697 - 703

← 1 2 3 4 5 6 7 8 9 10 →