Metabolic Syndrome

被引:516
作者
Samson, Susan L. [1 ]
Garber, Alan J. [1 ,2 ,3 ]
机构
[1] Baylor Coll Med, Dept Med, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Biochem & Mol Biol, Houston, TX 77030 USA
关键词
Metabolic syndrome; Obesity; Dyslipidemia; Hypertension; Cardiovascular risk; Diabetes risk; National Cholesterol Education Program Adult Treatment Panel III; CORONARY-HEART-DISEASE; FATTY LIVER-DISEASE; NUTRITION EXAMINATION SURVEY; DIABETES PREVENTION PROGRAM; POLYCYSTIC-OVARY-SYNDROME; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; ADIPOSE-TISSUE; RISK-FACTORS; NATIONAL-HEALTH;
D O I
10.1016/j.ecl.2013.09.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Metabolic syndrome is not a disease per se, but is a term that highlights traits that may have an increased risk of disease, approximately 2-fold for cardiovascular disease and 5-fold or more for type 2 diabetes mellitus. Obesity and insulin resistance are believed to be at the core of most cases of metabolic syndrome, although further research is required to truly understand the pathophysiology behind the syndrome and the gene-environment interactions that increase susceptibility. The mainstay of treatment remains lifestyle changes with exercise and diet to induce weight loss and pharmacologic intervention to treat atherogenic dyslipidemia, hypertension, and hyperglycemia.
引用
收藏
页码:1 / +
页数:24
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